Central giant cell granuloma (CGCG) is a benign jaw lesion predominantly found in the mandible of young female patients with a variable clinical behavior. Although surgical management is regarded as the main treatment modality for this lesion, the use of intralesional injections of steroids has been recently advocated for its treatment. In addition to this conservative management, the use of fi...

We report a 35-year-old mulatto female patient with neurofibromatosis Type 1 who presented with facial asymmetry. The patient had two lesions: florid cemento-osseous dysplasia associated with peripheral giant cell granuloma. She was referred for surgical treatment of the peripheral giant cell granuloma and the florid cemento-osseous dysplasia was treated conservatively by a multidisciplinary te...

Introduction: Giant cell lesions of the bone comprise a group of jaw bone pathologies. Different pathogeneses such as reactive, vascular or neoplastic have been proposed for these lesions. In addition, differentiating between aggressive and nonaggressive central giant cell granuloma (CGCG) of the jaws based on histopathologic features is still impossible and due to different treatment protocols...

Abstract A newly described entity called “calcified chondroid mesenchymal neoplasms” includes neoplasms with variable amounts of calcification and FN1 fusions [Liu et al, Mod Pathol 2021]. We report a case left temporal bone giant cell granuloma-like lesion that also shows an FN1-TEK fusion. Close monitoring MRI images after surgery has showed no recurrence. Case report: 33-year-old male develo...

Giant cell tumor of bone rarely occurs in the skull, particularly in the temporal bone, it is rarest one. They are very aggressive and have tendency to local recurrence and late malignant change with metastases. Multiple bits of grey-brown tissue were received in 10% formalin fixative. These were processed in histokinette, embedded in paraffin and blocks were made with the help of microtome, th...