some lesions in the oral cavity and mostly on gingiva have predominant predilection towards females, and mostly occur in the first four decades of life when changes in sex hormone levels in blood are obvious. the present study aimed to investigate the presence and distribution of estrogen and progesterone receptors in peripheral giant cell granuloma (pgcg), pyogenic granuloma (pg) and periphera...

leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. they produce testosterone leading to hyperandrogenism. we present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra sonography, and a rise of total and free serum testosterone. an ovarian source of androgen was suspected and a surgery performed. a diagnosis o...

The authors report on a rare case of metachronous, multicentric giant cell tumor of bone in a young woman. The first lesion occurred in the right fibular head at 26 years of age, which was surgically treated. Twenty-seven months later, the second lesion developed in the right rib, and the patient underwent an excision of the tumor. Histologically, both tumors showed typical appearance of conven...

Multicentric giant cell tumors represent less than 1% of all giant cell tumors of bones. We report a case of multicentric giant cell tumors around both the knee joints in a mentally and physically challenged adult male that resulted in rapidly progressive painful swelling, restricted mobility and, ultimately, fixed deformity. These tumors had typical radiological appearance and the diagnosis wa...

Giant cell tumor is a benign primary bone tumor. The phalangeal localization rare. It distinguished from other locations by the local aggressiveness of and high rate recurrence. We report one case 25-year-old right-handed nurse with no reported pathological history who complained about an ulcero-budding mass right little finger evolving year ago. She would have initially consulted bonesetter ta...

Primary bone tumors can be either benign or malignant considering their natural history and cellular morphology. Benign bone tumors are much more frequent than malignant ones although some of them like giant cell tumor of bone can behave just like a malignant one that means has the capacity for massive local destruction and remote metastasis. Giant cell tumor of bone in adult people has a very ...

The author reports a very rare and very unique urinary bladder carcinoma. This carcinoma occurred in a 68-year-old Japanese patient who underwent cystectomy for bladder tumor. The tumor was large polypoid and ulcerated one. Histologically, the tumor consisted of the following three elements: giant cell sarcomatoid carcinoma (70% in area), squamous cell carcinoma (20% in area), and papillary uro...

chondromyxoid fibroma (cmf) is a rare benign cartilaginous tumor with a predilection for the bones of lower extremities and about one fourth of the tumors involve the foot.radiologically, an eccentric lytic lesion with well defined margins is seen in the metaphysis of the bone. we hereby, report an 18 yr old young male who presented to orthopedic outpatient department, jn medical college, aliga...

Giant cell tumor of the small bones, particularly the carpal bones of the hand, is exceedingly rare. We present a case report of giant cell tumor of the capitate in a 24 year-old female with 10 years postoperative follow-up. Although carpal bones are extremely unusual location, orthopedic surgeons should always keep in mind that differential diagnosis must include giant cell tumor of bone whene...

INTRODUCTION Primary hyperparathyroidism is a common endocrine disorder characterized by elevated parathyroid hormone levels, which cause continuous osteoclastic bone resorption. Giant cell tumor of bone is an expansile osteolytic tumor that contains numerous osteoclast-like giant cells. There are many similarities in the radiological and histological features of giant cell tumor of bone and br...