Angiogenesis has been shown to be a potential therapeutic target for early stages of diabetic nephropathy in a number of animal experiments. Vascular endothelial growth factor (VEGF) is the main mediator for abnormal angiogenesis in diabetic glomeruli. Although beneficial effects of anti-VEGF antibodies have previously been demonstrated in diabetic animal experiments, recent basic and clinical ...

cystatin c is a 13 kd basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. the cystatin c gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin c by most cells. this protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. because of these ch...

Transition patterns between different sleep stages are analysed in terms of probability distributions of symbolic sequences for young and old subjects with and without sleep disorder. Changes of these patterns due to ageing are compared with variations of transition probabilities due to sleep disorder.

The study's purpose was to identify the mediating role of intention and the stages of change (SOC) in physical activity (PA) over a 6-month period using two models (theory of planned behavior [TPB] and TPB/SOC). Participants were 143 adults with physical disabilities (70.68% response rate; M age = 46.03). The TPB constructs, SOC (time 1), and PA (time 2) were assessed using standardized self-re...

introduction: kidney is one of the target organs in diabetes mellitus. diabetic nephropathy is a major cause of end stage-renal disease and resulting an increased in morbidity and mortality of effected individuals. since diabetes is a progressive disease, therefore early diagnosis leads to better treatment. in this study primary diagnostic parameters were the goal. materials and methods: in thi...

Objective:It was aimed to investigate sociodemographic features of chronic kidney disease patients, analyze difference these in early and advanced stage find correctable factors that may change course new solutions treatment follow-up. Materials & Methods:Predialysis 345 patients diagnosed with were retrospectively analyzed. Patients divided into stages. Glomerular Filtration Rate 30 ml / min d...