Granular lymphocytes (GLs) in patients with GL-proliferative disorders (GLPDs) are known to express the interleukin-2 receptor (IL-2R) p chain (p70-75) constitutively and to proliferate in response to stimulation with IL-2 via the p chain. In this report, we found that the anti-CD3 monoclonal antibody (MoAb) OKT3 could induce the proliferation of GLs from patients with T-cell lineage GLPDs (T-c...

Authors would like to thank the Institute of Education Sciences Universitat Politecnica de Valencia (Spain) for supporting Teaching Innovation Group e-MACAFI and financial support through PIME Project PIME/2018/B25 PIME/2018/B26

Spatial linear mixed-models, consisting of a covariate effect and Gaussian process (GP) distributed spatial random effect, are widely used for analyses geospatial data. We consider the setting where is nonlinear. Random forests (RF) popular estimating nonlinear functions but applications RF data have often ignored correlation. show that this impacts performance adversely. propose RF-GLS, novel ...

AIMS While abnormal resting LV GLS has been described in patients with chronic heart failure with preserved ejection fraction (HFpEF), its prognostic significance when measured during an acute heart failure hospitalization remains unclear. We assessed the association between left ventricular global longitudinal strain (LV GLS) and outcomes in patients hospitalized with acute HFpEF. METHODS AN...

In this paper we survey methods to control for regression model error that is correlated within groups or clusters, but is uncorrelated across groups or clusters. Then failure to control for the clustering can lead to understatement of standard errors and overstatement of statistical signi cance, as emphasized most notably in empirical studies by Moulton (1990) and Bertrand, Du o and Mullainath...

The Grid Location Service (GLS) is a location service which provides location information for a node in a mobile ad hoc network. GLS provides a mechanism for a node to track the location of other nodes in the network topology. A mobile ad hoc network (MANET) is an autonomous system of mobile routers (and associated hosts) connected by wireless links–the union of which form an arbitrary graph. T...

BACKGROUND Left ventricular (LV) systolic dysfunction is an important predictor of cardiovascular death. Global longitudinal strain (GLS) is a widely available echocardiographic technique proven to be more sensitive than conventional ejection fraction (EF) in detecting subtle changes in LV function. However, the prognostic value of GLS in patients with chronic kidney disease (CKD) is unknown. ...

BACKGROUND Patients with recovery of left ventricular ejection fraction (LVEF) remain at risk for future deterioration of LVEF. However, there are no tools to risk stratify these patients. We hypothesized that global longitudinal strain (GLS) could predict sustained recovery within this population. METHODS AND RESULTS We retrospectively identified 96 patients with a reduced LVEF <50% (screeni...

The present paper thoroughly explores second-best efficient allocations in an adverse selection insurance economy. We start from a natural extension of the classical model, assuming less than perfect risk perceptions. We propose first and second welfare theorems, by means of which we describe efficiencyenhancing policies. Notions of weak and strong adverse selection are promising for interpreti...

This paper analyzes the conditions under which consistent estimation can be achieved in instrumental variables (IV ) regression when the available instruments are weak, in the local-to-zero sense of Staiger and Stock (1997) and using the many-instrument framework of Morimune (1983) and Bekker (1994). Our analysis of an extended k-class of estimators that includes Jackknife IV (JIV E) establishe...