Gestational diabetes mellitus (GDM) is associated with a high risk of immediate and late adverse outcomes for mothers and their offspring (1–4). This risk correlates with the level ofmaternal hyperglycemia (5), and glucose-lowering interventions were reported to decrease the risk of some of these adverse outcomes (6). In many countries, including Israel, a two-step approach for GDM screening is...

G estational diabetes mellitus (GDM), defined as carbohydrate intolerance first diagnosed during pregnancy (1), is a common medical complication of pregnancy, affecting 1.1–14.3% of pregnant women depending on the ethnic and clinical characteristics of the population and the diagnostic test employed (2). Ever since O’Sullivan and Mahan (3) published their criteria for diagnosis of GDM using a 1...

The diabetes mellitus burden is growing in countries where tuberculosis (TB) and HIV-1 remain major challenges, threatening TB control efforts. This study determined the association between TB and diabetes/impaired glucose regulation in the context of HIV-1.A cross-sectional study was conducted at a TB clinic in Cape Town (South Africa). Participants were screened for diabetes and impaired gluc...

M e t h o d s Design: Randomized controlled trial (Australian Carbohydrate Intolerance Study in Pregnant Women [ACHOIS]). Allocation: {Concealed}†.* Blinding: Blinded {outcome assessors, data analysts, and data safety and monitoring committee; outcome assessors for shoulder dystocia were not blinded}†.* Follow-up period: Birth to hospital discharge. Setting: 16 hospitals in Australia. Patients:...

OBJECTIVE Although not formally supported by guidelines, random glucose testing (RGT) is frequently used to screen for gestational diabetes mellitus (GDM). Results on test accuracy are inconclusive. The aim of this study was to systematically review the literature and calculate summary estimates of accuracy measures of RGT as screening test for GDM. STUDY DESIGN Systematic review to identify ...

OBJECTIVE Diabetes is underdiagnosed. About one third of people with diabetes do not know they have it, and the average lag between onset and diagnosis is 7 yr. This report reconsiders the criteria for diagnosing diabetes and recommends screening criteria to make case finding easier for clinicians and patients. PARTICIPANTS R.M.B. invited experts in the area of diagnosis, monitoring, and mana...

G estational diabetes mellitus (GDM), defined as carbohydrate intolerance of variable degree with onset or first recognition during pregnancy, is the most common medical condition of pregnancy. GDM affects 190,000 (4–5%) of the 4 million births occurring annually in the U.S. and is associated with several maternal and infant complications (1). Worldwide, the three primary screening strategies f...

OBJECTIVE To compare the cost-effectiveness of 2 possible screening strategies for gestational diabetes mellitus (GDM) from the perspective of the New Zealand health system, developed as part of a gestational diabetes guideline. DESIGN A decision analytic model was built comparing 2-step screening (glycated haemoglobin (HbA1c) test at first booking and a 2 h 75 g oral glucose tolerance test (...

OBJECTIVE The purpose of this document is to briefly review the existing data regarding the effect of a diagnosis of gestational diabetes mellitus (GDM), the different screening and diagnostic practices for GDM, and, finally, outline the recommended options for GDM screening in Canada. OPTIONS Consideration has been given to the existing screening practices for GDM including universal screeni...