OBJECTIVE To assess the benefits and harms of targeting intensive versus conventional glycaemic control in patients with type 1 diabetes mellitus. DESIGN A systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. DATA SOURCES The Cochrane Library, MEDLINE, EMBASE, Science Citation Index Expanded and LILACS to January 2013. STUDY SELECTION Randomise...

Common modifiable risk factors such as unhealthy diet, physical inactivity and tobacco use associated with urbanization and lifestyle changes and an aging population, give rise to the intermediate risk factors such as overweight/obesity, hyperglycaemia, hypertension and hyperlipidaemia the stepping stones to the main chronic non communicable diseases (NCDs) such as heart disease, stroke, cancer...

BACKGROUND There is some evidence that plasma insulin levels might influence ovarian cancer risk. Glycaemic index (GI) and glycaemic load (GL) are measures that allow the carbohydrate content of individual foods to be classified according to their postprandial glycaemic effects and hence their effects on circulating insulin levels. Therefore, we examined ovarian cancer risk in association with ...

There are no published data regarding the overall dietary glycaemic index (GI) and glycaemic load (GL) of Australian children and adolescents. We therefore aim to describe the dietary GI and GL of participants of the 2007 Australian National Children's Nutrition and Physical Activity Survey (2007ANCNPAS), and to identify the main foods contributing to their GL. Children, aged 2-16 years, who pr...

OBJECTIVE Glycaemic index (GI) reflects the postprandial glucose response of carbohydrate-containing foods. A diet with lower GI may improve glycaemic control in people with diabetes. The purpose of the present study was to evaluate the change in outcomes following a behavioural intervention which promoted lower-GI foods among adults with diabetes. DESIGN A pre-test-post-test control group de...