Self-emulsifying compositions are the basis of oral drug delivery systems used to improve solubility and increase bioavailability active pharmaceutical ingredients that poorly soluble in aqueous medium gastric juice. Aim. To develop self-emulsifying using simvastatin as an ingredient. Materials methods. During development composition mixture, excipients, such solvents, co-solvents, surfactants ...

A new glyceryl derivative (Glyceryl-1-hexacosanoate) and a flavone derivative (methyletherapigenin) were isolated from the stem bark extract of Piptadenia africana, a western Cameroonian plant species. Common terpenes like sitosterol, beta-amyrin and eicosane were also isolated. These compounds were identified using physical and spectroscopic methods including mp, IR, (1)H and (13)C-NMR, DEPT, ...

The eMcacy of pretreatment on the dentin surface with an aqueous solution of glycery1 methacrylate {GM) was examined by measuring the wall-to-wall polymerization centraction of a light activated composite in a cylindrical dentin cavity, and by measuring the tensile bondi strength to a flat dentin surface. All of the tested dentin surfaces were cleaned with neutralized O.5M EDTA and treated with...

In a chromatographic partitioning (Silicic acid-Hyflosupercel 2:1, Chloroform-methanol) of •gphosphatide•h of BCG, the author obtained three main peaks (Kondo, 1960) containing varied amounts of phosphorus. Glyceryl monomycolate was reported to distribute in neutral fat (Aoyagi et al., 1960) and in Wax A, C (Tsumita, 1956). It was assumed by the author that the glyceryl monomycolate can be migr...

Two new glyceroglycolipids as well as three known ones were isolated from the glyceroglycolipids molecular species obtained from two less polar fractions of the MeOH extract of the plant Euphorbia nicaeensis All. using normal and reversed phase column flash chromatography. The structures of the isolated glyceroglycolipids were determined on the basis of chemical and spectroscopic evidences. Two...

Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi konsentrasi serta jumlah formula yang optimum dari Cetylstearyl alkohol dan glyceryl monostearat sebagai emulgator agar diperoleh sediaan dengan karakteristik fisik stabilitas baik. Untuk menentukan proporsi relative bahan-bahan digunakan dalam suatu formula, maka pada penelitian optimasi metode Simplex Lattice Design (SLD). Formula d...