INTRODUCTION Endoscopic skull base surgery allows minimal invasive therapy through the nostrils to treat infectious or tumorous diseases. Surgical and anatomical education in this field is limited by the lack of validated training models in terms of geometric and mechanical accuracy. We choose to evaluate several consumer-grade materials to create a patient-specific 3D-printed skull base model ...

Elastic ellipsoidal functions defined by the observed hydration patterns around the DNA bases provide a new basis for measuring the recognition of ligands in the grooves of double-helical structures. Here a set of knowledge-based potentials suitable for quantitative description of such behavior is extracted from the observed positions of water molecules and amino acid atoms that form hydrogen b...

nanocomposites based on polyamide 6 (pa6) and poly(ethylene-co-1-butene)-graft-maleic anhydride (eb-g-mah) blends have been prepared via melt mixing. the effect of blend ratio and organoclay concentration onthe crystallization and melting behavior of specimens were studied. three types of commercial organo-modifiedclay (cloisite 30b, cloisite 15a and cloisite 20a) were employed to assess the im...

The influence of polymeric dispersants containing different functional groups on TiO2 pigment particle suspension was investigated at pH 6.0 and 9.5, using rheology and particle size data. The dispersants chosen were polyacrylic acid and modified polyacrylamides including homo and copolymers modified with carboxylate and/or hydroxyl groups. The pigment suspension was strongly affected by both p...

BACKGROUND AND AIM The increasing number of surgical procedures performed with local anesthesia, followed by immediate patient discharge from the hospital, emphasizes the need for a tight waterproof suture that is capable of maintaining its tensile strength in the postoperative phase when the wound tumescence, edema due to the anesthetic drug, and surgical trauma disappear. Moreover, the issue ...

abstract soil crust decreases soil infiltration and prevents plant stablishment. thus reduction of crust effects is a prominent way to avert desertification. this study was conducted to investigate the effect of polyacrylamide on emergence of canola seedlings in a crusted soil and some physicochemical properties of soil such as ph, ec, sar and bulk density in a field located in date and tropica...

Three DNA binding polyamides () were synthesized that bind with high affinity (K(a) = 8.7. 10(9) m(-1) to 1.4. 10(10) m(-1)) to two 7-base pair sequences overlapping the Ets DNA binding site (EBS; GAGGAA) within the regulatory region of the HER2/neu proximal promoter. As measured by electrophoretic mobility shift assay, polyamides binding to flanking elements upstream () or downstream (2 and 3)...

Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor-DNA interfaces, and modulate gene expression pathways in cell culture experiments. In this paper we describe a high-resolution X-ray crystal structure of a β-amino turn-linked eight-ring cyclic Py-Im polyamide bound to the central six base ...

Background. Open wound treatment requires a use of bandage material to prevent the development pathogenic microflora and provide necessary conditions for tissue regeneration.
 The aim study was compare effectiveness polyacrylamide (PAA) dextran-graft-polyacrylamide (D-PAA) hydrogels loaded with silver nanoparticles (AgNPs), antibiotics, photosensitizers bacterial infection open wounds.&#x0...