Bloodstream infections are a leading cause of admissions to hospital intensive care units and carry a high mortality rate. Clinical outcome can be greatly improved by early effective antibiotic therapy; therefore, broad-spectrum antimicrobial therapy is often initiated when there is a clinical suspicion of bloodstream infection. Unfortunately, this method may not always be effective when dealin...

OBJECTIVE To document the risk of the development of vancomycin-resistant bacteria in a population of seriously burned patients during a 10-year period of common vancomycin hydrochloride use. DESIGN Retrospective study. SETTING The US Army Institute of Surgical Research, Burn Center, Fort Sam Houston, Tex. POPULATION AND METHODS Microbiology, infection, and antibiotic use records collecte...

results out of 2229 suspected meningitis cases, 255 (11.4%) were detected as positive culture. most of the isolates were gram-positive cocci, which 116 (45.5%) were staphylococcus epidermidis, and 20 (7.8%) identified as streptococcus spp. among gram-negative isolates, escherichia coli and acinetobacter spp., each with 19 isolates (5.9%), were predominant. overall, the most effective antibiotic...

BACKGROUND Infectious complications in tissue expander (TE) breast reconstruction can be devastating and costly. Therefore, to optimize care, we examined patient's demographics, microbiology of TE infections, and the efficacy of empiric antimicrobial regimens and thereafter generated an algorithm for the treatment of these complex infections. METHODS We retrospectively reviewed all patients w...

Nano structured materials have wide range of applications due to their interesting size-dependent chemical and physical properties compared to particles of size in the range of micrometer. Copper oxide nano materials are of interest on account of their potential uses in many technological fields. In this study  CuO nanoparticles were synthesized via simple sol gel method using basic CuSO4<...

Gram-positive anaerobic cocci (GPAC) are a heterogeneous group of organisms defined by their morphological appearance and their inability to grow in the presence of oxygen; most clinical isolates are identified to species in the genus Peptostreptococcus. GPAC are part of the normal flora of all mucocutaneous surfaces and are often isolated from infections such as deep organ abscesses, obstetric...

Sepsis is a life-threatening organ dysfunction caused by disturbed response to infection. The development of sepsis preceded Systemic Inflammatory Response Syndrome (SIRS), which the overall inflammatory body severe lesion. role opportunistic pathogens in CER and may be considered proven, but value intestinal microbiome remains underestimated. survey systematized data on cell wall or membrane c...