OBJECTIVE To study the effect of different phenolic compounds and red wine on pulmonary metastatic melanoma. METHODS Swiss mice were inoculated with 500000 melanocytes B16F10 and given oral doses of diosmin, grape seed extract (GSE) and red wine. A macroscopic count was made of the metastatic nodules on the lung surface and a microscopic study by image analysis of five sections, calculating t...

Purpose: The aim of the present study was to determine the ability of grape seed extract (GSE) as a powerful antioxidant in preventing adverse effect of doxorubicin (DOX) on heart function. Methods: Male rats were divided into three groups: control, DOX (2 mg/kg/48h, for 12 days) and GSE (100 mg/kg/24h, for 16 days) plus DOX. Left ventricular (LV) function and hemodynamic parameters were assess...

Jejunal biopsy specimens from patients with gluten-sensitive enteropathy (GSE) (obtained during gluten challenge) as well as from normal individuals and patients with other gastrointestinal abnormalities were cultured in vitro for 48 h in the presence or absence of a peptic-tryptic digest (P-T digest) of gliadin. In the absence of gliadin the alkaline phosphatase activity in the biopsy specimen...

The aim of the study was to test associations between self-reported access exercise in green spaces (GS) and moderate-to-vigorous physical activity (MVPA) testing mediating role motivation. Based on self-determination theory (SDT), we expected that self-determined motivation will mediate availability GS for exercising (GSE) MVPA with most regulation forms (identified intrinsic motivation) demon...

the effects of dietary supplementation of grape seed extract (gse) and vitamin c on carcass characteristics, gut morphology and ileal microflora in broiler chickens exposed to chronic heat stress were examined. experimental diets included a control diet (without additive), 3 levels of gse (150, 300, 450 mg/kg of diet), and vitamin c (300 mg/kg of diet). each of the five diets was fed to 5 repli...

OBJECTIVES To report on the responsiveness testing and clinical utility of the 12-item Geriatric Self-Efficacy Index for Urinary Incontinence (GSE-UI). DESIGN Prospective cohort study. SETTING Six urinary incontinence (UI) outpatient clinics in Quebec, Canada. PARTICIPANTS Community-dwelling incontinent adults aged 65 and older. MEASUREMENTS The abridged 12-item GSE-UI, measuring older ...

BACKGROUND Self-efficacy is needed for effectuating lifestyle changes, and it is therefore an important target related to health. The purpose of this study was to evaluate the psychometric properties of the General Self-Efficacy Scale (GSE) using Rasch analysis in a sample of adults with morbid obesity. METHODS A convenience sample of adults with morbid obesity was recruited from patient educ...

Grape seed extract (GSE) is a commonly available dietary supplement taken for the anti-oxidant activity that's attributed to its proanthocyanidin (oligomers of monomeric polyphenols) content. Similar polyphenol-enriched preparations from blueberries and soy have shown protection against ovariectomy-induced or age-related cognitive deficits, suggesting that the molecular changes induced by these...

The effect of grape seed extract (GSE) feed supplementation on performance, antioxidant enzyme activity, and immune responses in broiler chickens suffering from heat stress were investigated in this study. Experimental diets including control diet (with no additive), 3 levels of GSE (150, 300, 450 mg/kg), and one level of vitamin C (300 mg/kg) as a positive control were fed to the birds from 1 ...