OBJECTIVES plasmid pB1000 bearing bla(ROB-1) is responsible for high-level β-lactam resistance in Haemophilus influenzae as well as in Pasteurella multocida and Haemophilus parasuis isolates from Spain. Here, we explore the presence of ROB-1 in Italy and investigate the relative contribution of penicillin-binding protein 3 (PBP3) mutations and ROB-1 to the β-lactam resistance phenotype in H. in...

UV-irradiated plasmid pNov1 containing a cloned fragment of chromosomal DNA could be repaired by excision, but plasmid p2265 without homology to the chromosome could not. Establishment of pNov1 was more UV resistant in Rec(-) than in Rec(+) cells.

Pasteurella multocida appears to be a very rare cause of meningitis. The bacterium has morphological similarities with other causative organisms, particularly Haemophilus influenzae, and its apparent rarity may be due partly to misidentification. This case, only the fourth reported from the United Kingdom, could not be distinuished clinically from the meningitis, owing to other pyogenic bacteria.

A mouse model system was employed to investigate the temporal pattern of pulmonary clearance of Haemophilus influenzae and to evaluate the effect of the type b polysaccharide capsule on this clearance pattern. The lungs of BALB/c mice were inoculated with boluses of several different H. influenzae strains via an endobronchial catheter. A fully encapsulated H. influenzae type b strain multiplied...

Haemophilus haemolyticus has been recently discovered to have the potential to cause invasive disease. It is closely related to nontypeable Haemophilus influenzae (NT H. influenzae). NT H. influenzae and H. haemolyticus are often misidentified because none of the existing tests targeting the known phenotypes of H. haemolyticus are able to specifically identify H. haemolyticus Through comparativ...

A simple haemagglutination procedure is described which measures antibodies that react with capsular antigens of Haemophilus influenzae. Abnormally high antibody titres of appropriate type-specificity are common in the blood of human subjects who are known to have carried capsulate strains of H. influenzae. It is not yet clear whether all such antibodies are due to such carriage.

Epiglottitis is inflammation and cellulitis of the soft tissues above the glottis − the epiglottis, vallecula, arytenoid cartilage and aryepiglottic folds. It is a life-threatening emergency which is most commonly caused by the bacteria Haemophilus influenzae type b. The incidence of epiglottitis has declined dramatically since the introduction of the Haemophilus influenzae type b vaccine and c...

A rapid capillary tube method was used to demonstrate beta-lactamase production by ampicillin-resistant strains of Haemophilus influenzae.

Seizure is a rare but documented adverse event associated with ampicillin, which one of the most commonly used antibiotics in pediatrics. We report case 4-month-old male infant Haemophilus influenzae type A meningitis that experienced recurrent tonic-clonic seizures, possibly secondary to ampicillin treatment. After administration was withdrawn and antiepileptic agents were administered, seizur...

Escherichia coli katE gene product. Haemophilus influenzae is homologous to the A peroxide/ascorbate-inducible catalase from