High-throughput sequencing technologies are currently revolutionizing the field of biology and medicine, yet bioinformatic challenges in analysing very large data sets have slowed the adoption of these technologies by the community of population biologists. We introduce the 'Simple Fool's Guide to Population Genomics via RNA-seq' (SFG), a document intended to serve as an easy-to-follow protocol...

IR-visible sum-frequency generation (IV-SFG) vibrational spectroscopy and a molecular dynamics (MD) simulation were used to study the local layering order at the interface of 1-butanol-d9 and 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6), a room-temperature ionic liquid (RTIL). The presence of a local non-polar layer at the interface of the two polar liquids was successfully demon...

We use sum-frequency generation spectroscopy (SFG) in the infrared 2800–3000 cm−1 spectral range and UV–vis spectroscopy (transmission) in the 450–650 nm spectral range in order to characterize vibrational and electronic properties of various interfaces composed of organic monolayers adsorbed on gold nanoparticles (AuNPs) with 19 nm average diameter. SFG signal is observed for AuNPs films depos...

We have observed very strong magnetization-induced changes of the infrared-visible sum-frequency generation ~SFG! intensity from thin magnetic films using a free electron laser as a tunable infrared source. With the help of a magnetic grating a clear resonance is observed due to the excitation of surface plasmonpolaritons. The magnetization dependence of this resonance opens the way for nonline...

Nonlinear plasmonics requires the use of high-intensity laser sources in visible and near/mid-infrared spectral ranges to characterise potential enhancement vibrational fingerprint chemically functionalised nanostructured interfaces aimed at improving molecular detection threshold nanosensors. We used Two-Colour Sum-Frequency Generation (2C-SFG) nonlinear optical spectroscopy coupled European C...

This paper reports the latest development of The Halliday Centre Tagger (the Tagger), an online platform provided with semi-automatic features to facilitate text annotation and analysis. The Tagger features a web-based architecture with all functionalities and file storage space provided online, and a theory-neutral design where users can define their own labels for annotating various kinds of ...

Vibrational sum-frequency generation (SFG) spectroscopy of interfacial water at mineral/aqueous interfaces is extended to the near-IR range containing the low cross section stretch + bend combination bands (νcomb = νOH + δHOH) of liquid water at silica surfaces near 5000-5300 cm(-1), for the first time. The assignments of SFG spectra are supported by FTIR and Raman spectroscopic measurements of...

0009-2614/$ see front matter 2009 Elsevier B.V. A doi:10.1016/j.cplett.2009.01.028 * Corresponding author. Address: Department of C fornia, Berkeley, CA 94720, United States. E-mail address: [email protected] (P.L. Geissle We demonstrate a theoretical description of vibrational sum frequency generation (SFG) at the boundary of aqueous electrolyte solutions. This approach identifies and expl...

Ticks, including many that bite humans, are hosts to several obligate intracellular bacteria in the spotted fever group (SFG) of the genus Rickettsia. Only Rickettsia rickettsii, the agent of Rocky Mountain spotted fever, has been definitively associated with disease in humans in the United States. Herein we describe disease in a human caused by Rickettsia parkeri, an SFG rickettsia first ident...

Inhibiting inappropriate behavior and thoughts in the current context is an essential ability for humans, but the neural mechanisms for response inhibitory processing are a matter of continuous debate. The aim of this event-related functional magnetic resonance imaging (fMRI) study was to evaluate the negative blood oxygen level dependent (BOLD) effect on inhibitory processing during go/no-go p...