BACKGROUND With the introduction of laparoscopic antireflux surgery (LARS) for gastro-oesophageal reflux disease (GORD) along with the increasing efficacy of modern medical treatment, a direct comparison is warranted. The 3-year interim results of a randomised study comparing both the efficacy and safety of LARS and esomeprazole (ESO) are reported. METHODS LOTUS is an open, parallel-group mul...

A the Transport Area Open Meeting at IETF 70, area directors Magnus Westerlund and Lars Eggert noted that their queues are empty and that several Transport Area working groups are nearing completion. It may therefore be an opportune time to step back and consider possible directions for new projects in the Transport Area. !is article summarises some of the ideas presented and discussed at that ...

Slotting allowances are fees paid by manufacturers to get access to retailers’ shelf space. Both in the USA and Europe, the use of slotting allowances has attracted attention in the general press as well as among policy makers and economists. One school of thought claims that slotting allowances are efficiency enhancing, while another school of thought maintains that slotting allowances are use...

The purpose of model selection algorithms such as All Subsets, Forward Selection, and Backward Elimination is to choose a linear model on the basis of the same set of data to which the model will be applied. Typically we have available a large collection of possible covariates from which we hope to select a parsimonious set for the efficient prediction of a response variable. Least Angle Regres...

The purpose of this study was to assess the outcomes of posterior cruciate ligament (PCL) reconstruction using the Ligament Augmentation and Reconstruction System (LARS) (JK Orthomedic Ltd, Dollard-des-Ormeaux, Quebec, Canada) artificial ligament. Compared with older artificial ligaments, the LARS, which has been used in Europe for 15 years, is more resistant to wear and tear, has satisfactory ...

We show that there is a Bore1 measurable selection of Paretian utilities in ‘markets with a continuum of traders’. Theorem: Let T and X be Polish spaces, R a Bore1 subset of T x X xX, and B={(t,x): (t,x,x)ER}. Suppose that for each t, R,={(x,y): (t,x,y)ER} is a preference order on B, = {x: (t,x) EB). Then there is a Bore1 measurable function f: B-$0, l] such that for all t E IT; f,: B,+[O, I] i...

endogenous b-catenin aggravates acute kidney injury in mice. Kidney Int 82: 537–547, 2012 13. Terada Y, Tanaka H,Okado T, ShimamuraH, Inoshita S, KuwaharaM, Sasaki S: Expression and function of the developmental gene Wnt-4 during experimental acute renal failure in rats. JAmSocNephrol14: 1223–1233, 2003 14. Cerpa W, Toledo EM, Varela-Nallar L, Inestrosa NC: The role of Wnt signaling in neuropro...

This paper proposes Maximal Associated Regression (MAR), a novel algorithm that performs forward stage-wise regression by applying nonlinear transformations to fit predictor covariates. For each predictor, MAR selects between linear or additive as determined the dataset. The proposed is an adaptation of Least Angle (LARS) and retains its efficiency in building sparse models. Constrained penaliz...