Encephalitis causes high rates of illness and death, yet its epidemiology remains poorly understood. To improve incidence estimates in England and inform priority setting and treatment and prevention strategies, we used hospitalization data to estimate incidence of infectious and noninfectious encephalitis during 2005-2009. Hospitalization data were linked to a dataset of extensively investigat...

background: orang primary health centre (ophc) and balipara primary health centre (bphc) of assam (india) report mosquito borne diseases annually. current study was performed to ascertain the prevalence of known malaria and japanese encephalitis (je) vectors and their possible role in disease transmission. methods: malaria epidemiological data for 2006–2010 and je data for 2008–2013 of assam, i...

in this case we present a previously healthy child with sudden behavioral change and acute confusional state (acs). acs is a neurologic emergency. the clinical manifestations of acs are; confused affect, limited verbal response, disturbance in performing orders, some automatism, stable vital signs and absence of tonic-clonic movements and it has a wide range of differential diagnosis which shou...

backgrund: free-living amoebae belonging to the genus acanthamoeba have an environmental distribution. amoebic keratitis due to these protozoan parasites continue to rise in iran and worldwide. in iran, there are various researches regard-ing both morphological and molecular identification of acanthamoeba spp. in envi-ronmental and clinical samples. however, there is no thorough review about ac...

abstract: herpes simplex encephalitis (hse) is a life threatening outcome of herpes simplex virus (hsv) infection of the central nervous system (cns). hsv accounts for 2-5 percent of all cases of encephalitis. one third of cases occur in those younger than 20 years old and one half in those older than 50 years old. clinical diagnosis is recommended in the encephalopathic, febrile patients with ...

BACKGROUND Despite the discovery of CSF and serum diagnostic autoantibodies in autoimmune encephalitis, there are still very limited CSF biomarkers for diagnostic and monitoring purposes in children with inflammatory or autoimmune brain disease. The cause of encephalitis is unknown in up to a third of encephalitis cohorts, and it is important to differentiate infective from autoimmune encephali...

BACKGROUND Encephalitis rates by etiology and acute-phase outcomes for encephalitis in the 21st century are largely unknown. We sought to evaluate cause-specific rates of encephalitis hospitalizations and predictors of inpatient mortality in the United States. METHODS Using the Nationwide Inpatient Sample (NIS) from 2000 to 2010, a retrospective observational study of 238,567 patients (mean [...

BACKGROUND Herpes simplex virus (HSV) encephalitis is a life-threatening infection of the brain, which has significant physical, cognitive and social consequences for survivors. Despite increasing recognition of the long-term effects of encephalitis, research and policy remains largely focused on its acute management, meaning there is little understanding of the difficulties people face after d...

PURPOSE In people with suspected inflammatory CNS disease, cerebrospinal fluid (CSF) is commonly analyzed. Antibody-associated limbic encephalitis (ab-LE) and anti-NMDAR-encephalitis are recognized as two major syndromes of autoimmune epilepsies. Here, we investigated the diagnostic value of CSF findings in these two entities. METHODS We reviewed patients from our tertiary epilepsy centre wit...

Knut the polar bear of the Berlin Zoological Garden drowned in 2011 following seizures and was diagnosed as having suffered encephalitis of unknown etiology after exhaustive pathogen screening. Using the diagnostic criteria applied to human patients, we demonstrate that Knut's encephalitis is almost identical to anti-NMDA receptor encephalitis which is a severe autoimmune disease representing t...