introduction: thalassemia is common in iran. appropriate therapy for this disease includes a regular blood transfusion and chelation therapy. however, patients will inevitably confront with side effects, particularly iron overloads in critical organ including heart, ductless glands and liver. this study tries to determine the prevalence of diabetes mellitus in transfusion dependent β thalassemi...

Corresponding author: Seok Man Son Department of Internal Medicine, Pusan National University School of Medicine, and Diabetes Center and Endocrine Clinic, Pusan National University Yangsan Hospital, 20 Geumo-ro, Yangsan 626-787, Korea E-mail: [email protected] The mechanisms underlying the association of type 2 diabetes mellitus (T2DM) with vascular dysfunction are complex. Classical cardiovas...

Effect of In order to test the memory state in patients with non-insulin dependent diabetes mellitus (NIDDM) after glycemic control, one-hundred patients referring to Isfahan Endocrine and Metabolism Research Center were simply randomized. They were compared in point of memory state with one hundred cases as the control group. The Wechsler Memory Scale test was utilized to evaluate the mem...

Lowering the glucose level in diabetic patients reduces the risk of many consequences which are usually reported in these patients. Non-insulin dependent (type II) diabetes which cannot be controlled with sulfonylureas alone can be controlled with a combination of sulfonylurea and insulin. In an open randomized trial 58 patients were divided into three groups. The fIrst group received only ...

Type 2 diabetes mellitus is an increasingly prevalent condition worldwide. The complications of this disease are known to significantly increase the morbidity and mortality of those affected, resulting in substantial direct and indirect costs. Although good glycemic control has been shown to reduce the incidence and progression of diabetes-related microvascular complications, blood glucose leve...

BACKGROUND Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is an important risk factor for the occurrence of diabetes complications. The prevalence of celiac disease (CD) is high in type 1 diabetes mellitus however, there are scarce data a...

OBJECTIVE Gene expression alterations, especially in target tissues of insulin, have been associated with type 2 diabetes (T2D). In this study, we examined if genes involved in oxidative phosphorylation (OXPHOS) show differential gene expression and DNA methylation in pancreatic islets from patients with T2D compared with non-diabetic donors. DESIGN AND METHODS Gene expression was analyzed in...

BACKGROUND The purpose of this study was to assess diabetes distress and its related factors among type 2 diabetic patients to better tailor intervention planning in Isfahan-Iran. METHODS A cross-sectional study was conducted in 2011. Study population was patients with type 2 diabetes referring to Omolbanin, an outpatient diabetic center in Isfahan. 140 diabetic patients met the inclusion cri...