Soils contaminated with hexachlorocyclohexanes (HCHs) are a legacy of the heavy use lindane during 20th century. This pesticide production generated large amounts residues other HCH isomers, which were habitually mismanaged. The sediments treated in this work (coming from an old landfill) example environmental problem global dimensions. efficient remediation these sediments, mainly β-HCH (99 mg...

BACKGROUND Hydroxychavicol (HCH), a constituent of Piper betle leaf has been reported to exert anti-leukemic activity through induction of reactive oxygen species (ROS). The aim of the study is to optimize the oxidative stress -induced chronic myeloid leukemic (CML) cell death by combining glutathione synthesis inhibitor, buthionine sulfoximine (BSO) with HCH and studying the underlying mechani...

Levels of six PCB congeners and seven organochlorine pesticides were investigated and compared in ambient air and in pine needle samples. The applied methods are suitable for the analysis of PCBs and organochlorine pesticides in environmental samples and for their detection in recent intakes. DDE, HCB, lindane, PCB-28, PCB-52, PCB-101, PCB-138 and PCB-153 were found in all pine needle and air s...

Organochlorine pesticides such as DDT and HCH had been abundantly produced and used since the around twentieth century in all over the world and environmental pollution, food contamination and human body pollution had developed into social problem because of their high bioconcentration potential and high persistency. The use and manufacturing of DDT and HCH were forbidden in many countries incl...

d-Hexachlorocyclohexane (d-HCH), a lipophilic neurodepressant agent, has been shown to inhibit neurotransmitter release and stimulate ryanodine-sensitive Ca channels. However, the effect of d-HCH on neuronal activity remains unclear, although it may enhance the g-aminobutyric acid-induced current. Its effects on ionic currents were investigated in rat pituitary GH3 cells and human neuroblastoma...

Harbour seals and grey seals from Faxaflói (Western Iceland) were analyzed for contamination with organochlorines (HCB, PCBs, p,p'-DDT,p,p'-DDE, chlordanes and the enantiomers of alpha-HCH). Although the values strongly varied, both harbour seals and grey seals on averaged showed comparable levels of PCBs, p,p'-DDT, p,p'-DDE and alpha-HCH, as well as chlordanes (sigma CD). Differences were meas...

Little is known about the association between the single nucleotide polymorphisms (SNPs) and haplotypes of the dedicator of cytokinesis 7 (DOCK7), pro-protein convertase subtilisin/kexin type 9 (PCSK9) and polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) and serum lipid traits in the Chinese populations. This study was to determine the association between nine SNPs in the three genes an...

As part of the Global Atmospheric Passive Sampling (GAPS) study, XAD-resin based passive samplers are being deployed for consecutive one-year periods at numerous sites on all seven continents to determine annually averaged concentrations of persistent organic pollutants. Concentrations of banned organochlorine pesticides as well as a number of current-use pesticides in samples from the first fo...