AIM To analyse local tumour control, radiation related complications, visual acuity, enucleation rate, and survival after brachytherapy of small to medium sized choroidal melanoma (CM) with a high dose rate (HDR) strontium-90 (Sr-90) applicator. METHODS From 1983 until 2000, 98 eyes with CM were treated with Sr-90 brachytherapy. The main outcome measures were actuarial rates of the patients' ...

PURPOSE Dysphagia is a common initial presentation in locally advanced esophageal cancer and negatively impacts patient quality of life and treatment compliance. To induce fast relief of dysphagia in patients with potentially operable esophageal cancer high-dose-rate (HDR) brachytherapy was applied prior to definitive radiochemotherapy. MATERIAL AND METHODS In this single arm phase II clinica...

This paper compares the isotopes (60)Co and (192)Ir as radiation sources for high-dose-rate (HDR) afterloading brachytherapy. The smaller size of (192)Ir sources made it the preferred radionuclide for temporary brachytherapy treatments. Recently also (60)Co sources have been made available with identical geometrical dimensions. This paper compares the characteristics of both nuclides in differe...

BACKGROUND AND PURPOSE High dose rate (HDR) brachytherapy is a highly extended practice in clinical brachytherapy today. Quality dose rate distribution datasets of the HDR sources used in a clinical treatment are required. Because of the different source designs, a specific dosimetry dataset is required for each source model. In the recently published BRAPHYQS-ESTRO Report, an overview of avail...

The aim of this pictorial essay is to present the mould based HDR brachytherapy technique used at the Holycross Cancer Center for penile cancer patients. We use images to describe this method step by step.

PURPOSE To investigate the use of optically stimulated luminescent dosimeters (OSLDs) for high dose rate (HDR) Ir-192 brachytherapy. While common in megavoltage radiotherapy applications, the performance of OSLDs using kilovoltage energies, high dose gradient and high dose rate regions ubiquitous to HDR has not been demonstrated. METHODS Commercially available nanoDotTM (Landauer, Glenwood, I...

Purpose Intraoperative radiation therapy (IORT), delivered by intraoperative electron beam (IOERT) or high-dose-rate brachytherapy (HDR-IORT), may reduce the local recurrence rate in patients with locally advanced and recurrent rectal cancer (LARC LRRC, respectively). The aim of this study was to compare oncological outcomes between both IORT modalities LARC LRRC who underwent a microscopic irr...

In patients with advanced or metastatic lung cancer who present predominantly with dyspnoea and haemoptysis the use of HDR brachytherapy has been proven an effective method of palliation. The application of brachytherapy as a boost to EBRT in curative cases is much more restricted. It can be considered in a selected group of patients with dominating endobronchial disease, who are medically inop...

Fricke-gel layer dosimeters (FGLD) and Fricke gel dosimetric catheters (FGDC) have been designed and tested with the aim of enquiring their suitability for HDR Ir brachytherapy source control and for in-vivo dose verification during treatment. Anisotropy function measurements have been carried out with FGLDs in which a thin plastic tube has been placed in for the Ir source insertion. FGDCs are ...

The high dose gradients near the source characteristics of brachytherapy are equivalent to nefarious effects if unnoticed errors take place during patient treatment. In vivo dosimetry is only method quantify delivered dose. Previous studies this one, have characterized potential detectors that can be used as in dosimeter. Some them focused on tracking topic HDR brachytherapy. aim study perform ...