In Caenorhabditis elegans small RNAs can regulate genes across generations. The mysterious tendency of heritable RNA interference (RNAi) responses to terminate after 3-5 generations has been referred to as "the bottleneck to RNAi inheritance." We have recently shown that the re-setting of epigenetic inheritance after 3-5 generations is not due to passive dilution of the original RNA trigger, bu...

A substantial body of research has demonstrated links between poverty and family structure from one generation to the next, but has left open key questions about the implications of these associations for aggregate-level change. To what extent does intergenerational inheritance affect trends in poverty and single parenthood over time and, in particular, trends in the relative economic positions...

In this paper we present the BandWidth Inheritance (BWI) protocol, a new strategy for scheduling real-time tasks in dynamic systems, which extends the resource reservation framework to systems where tasks can interact through shared resources. The proposed protocol provides temporal isolation between independent groups of tasks, and enables a schedulability analysis for guaranteeing the perform...

In this paper we describe the encoding of a Unification-Based Generalised Categorial Grammar for English, in terms of a default inheritance network of types, implemented with YADU, which is an order independent default unification operation on typed feature structures. We then propose to use this framework to encode a Universal Grammar (UG) and associated parameters, following the Principles an...

Polyploidy can result in both evolutionary dead-ends and successful evolutionary transitions. A pair of recent papers indicates that adapting meiosis is a necessary step on the way to becoming a successful polyploid.

tactics and pragmatism he displayed. But Bevan's accomplishment, formidable as it was, has to be put in proper perspective. Unlike Lloyd George in 1911, Bevan had the backing of a movement that already had force. Does Webster deny that? If so, he takes issue with Bevan himself for this is what the Minister had to say when he introduced the Health Service Bill in 1946: "The first reason why a he...

Inheritance provides object-oriented programming with much of its great reusability power. When inheritance is single, its specifications are simple and everybody roughly agrees on them. On the contrary, multiple inheritance yields ambiguities that have prompted long-standing debates and no two languages agree on its specifications. In this paper, we present a semantics of multiple inheritance ...

tactics and pragmatism he displayed. But Bevan's accomplishment, formidable as it was, has to be put in proper perspective. Unlike Lloyd George in 1911, Bevan had the backing of a movement that already had force. Does Webster deny that? If so, he takes issue with Bevan himself for this is what the Minister had to say when he introduced the Health Service Bill in 1946: "The first reason why a he...