We present an experimental validation of the distorted Born iterative method with two-step shrinkage thresholding (DBIM-TwIST) algorithm for problem brain stroke detection and differentiation, using anatomically accurate, multi-layer head phantom. To this end, we have developed a gelatine-based, complex phantom which mimics various tissues also includes target mimicking hemorrhagic or ischemic ...

  Introduction: Geometric distortion is a major shortcoming of magnetic resonance imaging (MRI), which has an important influence on the accuracy of volumetric measurements, an important parameter in neurology and oncology. Our goal is to design and construct a new three- dimensional phantom using a 3D printer in order to measure geometric distortion and its reproducibility in...

SPECT detects γ-rays from administered radiopharmaceutical within the patient body. γ-rays pass through different tissues before reaching detectors and are attenuated. Attenuation can cause artifacts; therefore different methods are used to minimize attenuation effects. In our study efficacy of Chang method was evaluated for attenuation purpose, using a custom made heart phantom. Due to d...

background: the purpose of this study is to fabricate inexpensive in-house low cost homogeneous and heterogeneous human equivalent thorax phantom and assess the dose accuracy of the treatment planning systems (tps) calculated values for different lung treatment dosimetery. it is compared with thermoluminescent dosimeter (tld) measurement. materials and methods: homogeneous and heterogeneous tho...

background: radiotherapy plays an important role in the management of most malignant and many benign primary central nervous system (cns) tumors. radiotherapy affects both tumor cells and uninvolved normal cells; so, it is important to estimate absorbed dose to organs at risk in this kind of treatment. the aim of this study was to determine the absorbed dose to chiasma, lens, optic nerve, retin...

background: this study assessed the clinical usefulness of the solid phantom, which may compensate for the disadvantages of the water phantom, by comparing the radiological doses between the two depending on their depths. materials and methods: the experimental equipment used was a linear accelerator for medical use, water phantom, solid phantom, farmer type ion chamber and electrometer. the di...

Background: Photon attenuation as an inevitable physical phenomenon influences on the diagnostic information of SPECT images and results to errors in accuracy of quantitative measurements. This can be corrected via different physical or mathematical approaches. As the correction equation in mathematical approaches is nonlinear, in this study a new method of linearization called ‘Piece Wise Line...

OBJECTIVE Over the past few years, we have performed several brain SPECT studies on patients who have had previous head trauma that required metallic cranioplasty. Transaxial images showed clearly defined photon-deficient areas extending from the brain tissue into the area of the scalp. To investigate the extent and pattern of this type of artifact, SPECT brain phantom studies were performed an...