Fulminant hepatic failure (FHF) is a clinically severe type of liver injury with an extremely high mortality rate. Although the pathological mechanisms of FHF are not well understood, evidence suggests that the complement system is involved in the pathogenesis of a variety of liver disorders. In the present study, to investigate the role of complement in FHF, we examined groups of mice followin...

UNLABELLED Orthotopic liver transplantation is the only proven effective treatment for fulminant hepatic failure (FHF), but its use is limited because of organ donor shortage, associated high costs, and the requirement for lifelong immunosuppression. FHF is usually accompanied by massive hepatocellular death with compensatory liver regeneration that fails to meet the cellular losses. Therefore,...

The study assessed the quantity and value of food crop outputs of the gender categories in the Anambra state. At this research estimated the quantity and energy content of food stuffs consumed as well as required by each gender headed households, estimated the extent and magnitude of food security and insecurity in the area among the gender categories and examined the determinants of food secur...

the study assessed the quantity and value of food crop outputs of the gender categories in the anambra state. at this research estimated the quantity and energy content of food stuffs consumed as well as required by each gender headed households, estimated the extent and magnitude of food security and insecurity in the area among the gender categories and examined the determinants of food secur...

the present research aims to compare the impact of group consultation on the basis of two approaches of reality therapy and feminism over the identity changes of householder women. statistical society has been the whole community of householder women who receive support from imam khomeini relief committee in fifth district of tehran, which was randomly selected. research tool has been indigenou...

Background and Aim: Family female heads are one of the most vulnerable groups in the society and empowering them is essential. This research was a systematic study to design and develop a model of educational needs of female heads in the female-headed households. Materials and Methods: This study was a qualitative applied research of a research synthetic type conducted using content-analysis ...

Compared to children in male-headed traditional families where their natural parents are married to each other, children living in female-headed single-parent, lesbian or other environments where they are deprived of their natural fathers are: 1. Eight times more likely to go to prison. 2. Five times more likely to commit suicide. 3. Twenty times more likely to have behavioral problems. 4. Twen...

OBJECTIVE To identify the risk factors for fulminant hepatic failure (FHF) and their relation with the outcome in children. METHODS Descriptive case study was conducted at National Institute Of Child Health. Fifty patients having clinical and biochemical markers suggestive of FHF were included in this study and data was extracted from files, retrospectively. Their outcome was noted as expiry ...

The liver has a remarkable regenerative capacity, allowing recovery following injury. Regeneration after injury is contingent on maintenance of healthy residual liver mass, otherwise fulminant hepatic failure (FHF) may arise. Understanding the protective mechanisms safeguarding hepatocytes and promoting their proliferation is critical for devising therapeutic strategies for FHF. We demonstrate ...

Action potential generation is governed by the opening, inactivation, and recovery of voltage-gated sodium channels. A channel's voltage-sensing and pore-forming α subunit bears an intrinsic fast inactivation particle that mediates both onset of inactivation upon membrane depolarization and rapid recovery upon repolarization. We describe here a novel inactivation particle housed within an acces...