Cardiac mechanics is primarily described by the pressure-volume relationship. The ventricular loop displays instantaneous relationship between intraventricular pressure and volume throughout cardiac cycle; however, it does not consider shape of ventricles, their spatiotemporal deformation patterns, how these balance with flowing blood. Our study demonstrates that represents a first level approx...

What is believed to be the first known case of heart-block arising in a dog as a result of an ingenerate pathological lesion is here reported. The auriculo-ventricular dissociation was of that degree known as relatively complete block and became apparent on section of the right vagus nerve. Stimulation of the peripheral end of the cut vagus failed to inhibit the ventricles, although complete in...

The natriuretic peptides (NP) appear to be functional by midgestation, respond to volume stimuli, and regulate blood pressure and salt and water balance in the developing embryo. In addition, the NP may help regulate the blood supply to the fetus, acting as vasodilators in the placental vasculature. Peaks of ANP and BNP expression during gestation coincide with significant events in cardiac org...

A biventricular model, which coupled the electrical property and mechanical property of the heart, was constructed and the ventricular wall motion and deformation have been simulated based on this model. The biventricular mechanical model was constructed based on composite material theory and finite element method. The excitation propagation was simulated by electrical heart model, and the resu...

Heart failure is a leading cause of death in New Zealand. In order to determine the causesof rhythm disturbances leading to failure a knowledge of the structure and mechanical behaviour of cardiac tissue is important. This paper presents realistic stress and strain distributions for the passive heart that have been reproduced using a three-dimensional finite element model of the ventricles base...

The CardioWest Total Artificial Heart (CW-TAH) is a pneumatically driven pump that completely replaces the patient’s native ventricles orthotopically. The device weighs 160 g and consists of two artificial ventricles, four Medtronic Hall tilting disk valves, two membranes, and two drivelines tunneled through the skin, which connect the ventricles to an external console generating pulsatile flow...

Ventricular tachycardia like ventricular parasystole is rarely observed in the absence of cardiac disease (Massie and Walsh, 1960; Scherf and Bornemann, 1961), though several cases of functional ventricular tachycardia without demonstrable heart disease have been reported by Hair, Eagan, and Orgain (1962) and others. Parasystole consists of simultaneous activity of two independent impulse-formi...