Background: Cancer refers to the abnormal growth of cells and is still the most common cause of morbidity in world. The purpose of this study was to determine cytotoxicity effect of high molecular weight (HMWC) and low molecular weight of chitosan (LMWC) on three cancerous cell lines MCF-7, HeLa and Saos-2 with different histological origin. Methods: The anticancer property of two types of chi...

Objective(s) Nonviral vector can be an attractive alternative to gene delivery in experimental study. In spite of some advantages in comparison with the viral vectors, there are still some limitations for efficiency of gene delivery in nonviral vectors. To determine the effective expression, the recombinant Escherichia coli lacZ genes were cloned into the different variants of pcDNA3.1 and the...

Scheme of GO detection and mapping inside single HeLa cells by using label-free Raman spectroscopy with MCR analysis.

Introduction: One of the combination therapies for the treatment of cancer is ultrasound with other agents, which has received considerable attention in recent years. Ultrasound causes cavitation phenomenon that can produce some effects, such as; Reactive Oxygen Species (ROS), which results in damage to cancer cells. When a particle is in liquid, the cavitation threshold decrea...

We describe the synthesis of monodispersed, silica encapsulated conjugated polymer nanoparticles, their colour tunability and use in imaging HeLa cells.

It has been reported that several conifers possess cytotoxic activities on some human tumor cell lines. Taxol as a natural cytotoxic compound has been extracted from this family. In a program to screen the cytotoxic effects of natural resources, male and female branchlets, fruit or bark of two different species of Iranian conifers were collected, identified and the cytotoxic effects of their hy...

introduction: the aim of this study was to determine a proper cell line for adherance of helicobacter pylori and a suitable method for attachment of this bacteria to cell lines in vitro. material and methods: a total of 22 h.pylori strains,isolated from the antral biopsies of 49 patients with dyspepsia,gastritis,gastric ulcer,duodenal ulcer, etc., were evaluated by elisa(upr)to determine the di...

background & aim:cervical cancer is the most common   female genital cancer and the second most common cancer in women in the   world. since the herbal ingredients have been used for centuries to treat   cancer, purpose of the present study was to determine the cytotoxic   effect of hydroalcoholic extract from satureja bachtiarica bungeon   hela cancer cells line. experimental: hela cells line ...