Resin-based dental restorative materials contain allergenic methacrylate monomers, which may be released into saliva after restorative treatment. Monomers from resin-based composite materials have been demonstrated in saliva in vitro; however, studies analyzing saliva after restorative therapy are scarce. The aim of this study was to quantify methacrylate monomers in saliva after treatment with...

Bioactive films were produced by conjugation of a short peptide onto modified cellulose nanofibrils (CNF). Specifically, a hydrophilic copolymer, poly(2-aminoethyl methacrylate hydrochloride-co-2-hydroxyethylmethacrylate) (poly(AMA-co-HEMA)), was grafted via surface initiated polymerization from an initiator coupled to CNF. The poly(AMA-co-HEMA) was used as a spacer and support layer for immobi...

To develop a self-etching primer for ground dentin, 4-acryloxyethyltrimellitic acid (4-AET) was newly synthesized, and the effect of concentrations varying from 0 (control) to 56.5 wt% 4-AET in the water/ HEMA primer on bonding to the dentin was investigated. Bond strength to the dentin was significantly affected by the inclusion of 4-AET in the primer which also contained N,N-di(hydroxyethyl)-...

N,N-dihydroxyethyl methylacrylamide (DHEMAA), which is a methacrylate modified by diol, has been prepared by reaction of diethylanol amine with methyl methacrylate. UV curable urethane methacrylate oligomers have been synthesized by the reaction of a series of diol, triol, DHEMAA and HEMA with TDI or IPDI in two reaction orders. The first reaction style is the TDI or IPDI reacted with HEMA firs...

Water and solute or drug transport in crosslinked polymeric materials was investigated to determine the effects of polymer morphology, composition and solute properties on transport behavior. Two crosslinked polymer systems, poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) (P(HEMA-co-MMA)) and poly(vinyl alcohol) (PVA), were used in water transport and solute release experiments. Struct...

The drying kinetics were examined in four cross-linked polymers that form hydrogels: 2,3-Dihydroxypropyl methacrylate (DHPMA) and 2-hydroxyethyl methacrylate (HEMA) and two random copolymers, with one-to-one and three-to-one HEMA-to-DHPMA molar ratios. The hydrogels were saturated with buffered, isotonic saline solution and deionized water; weight loss kinetics were monitored at temperatures fr...

Polymerized resin-based materials are successfully utilized in medical applications. One draw- back is the release of monomers from the matrix due to an incomplete polymerization or degradation processes. Released monomers can diffuse in the systemic circulation and induceadverse effects to biological tissues. Although there are many hypotheses about the induction of cell death by resin monomer...

AIM Published clinical series suggest the osteoodontokeratoprosthesis (OOKP) may have a lower extrusion rate than current synthetic keratoprostheses. The OOKP is anchored in the eye wall by autologous tooth. The authors' aim was to compare adhesion, proliferation, and morphology for telomerase transformed keratocytes seeded on calcium hydroxyapatite (the principal mineral constituent of tooth) ...

Previous studies have shown a wide range of pulpal reactions to dentin bonding systems and a poor correlation between in vitro and in vivo toxicity of dentin bonding agents. Because dentin bonding agents are composed of multiple components which may diffuse through dentin, we hypothesized that these components may cause cytotoxicity through interactive (synergistic) effects. We investigated the...

In Human Erythroid Massive Amplification (HEMA) cultures, AB mononuclear cells (MNC) generate 1-log more erythroid cells (EBs) than the corresponding CD34(pos) cells, suggesting that MNC may also contain CD34(neg) HPC. To clarify the phenotype of AB HPC which generate EBs in these cultures, flow cytometric profiling for CD34/CD36 expression, followed by isolation and functional characterization...