We report a case of Klippel-Trenaunay-Weber syndrome in a 31-year-old woman who presented with hypertrophy of the left leg. She had severe osteoarthritic changes in the left hip joint secondary to the lack of acetabular coverage of the femoral head as the result of lateral inclination of the pelvis owing to leg-length discrepancy of 4 cm. The centre-edge angle (coverage ratio of the acetabulum ...

Cowden syndrome (CS), also known as multiple hamartoma-neoplasia syndrome, is an autosomal dominant disease with numerous possible clinical manifestations. Commonly present are skin changes including acral keratoses and facial trichilemmomas, as well as oral papillomas and scrotal tongue. There is an increased risk of malignancies including breast, thyroid, and endometrial cancers. Hamartomas m...

BACKGROUND There are many causes for a large lower limb in the pediatric age group. These children are often mislabeled as having lymphedema, and incorrect diagnosis can lead to improper treatment. The purpose of this study was to determine the differential diagnosis in pediatric patients referred for lower extremity "lymphedema" and to clarify management. METHODS The authors' Vascular Anomal...

Wilms tumor is the most common childhood renal tumor accounting for about 6% of pediatric malignant disease. Most patients with Wilms tumor can be cured with treatment and subsequently lead normal life. The multidisciplinary management of Wilms tumor has resulted striking improvement in survival of more than 85% nowadays and has become a paradigm for successful cancer therapy. We describe the r...

In 1953 Silver et al. described two children with abnormally short stature who had low birthweights and congenital asymmetry, or hemihypertrophy. Silver in 1964 reviewed 29 cases (see also Reister and Scherz, 1964; Moseley, Moloshok and Freiberger, 1966). In 1954, Russell independently described 5 children with short stature and low birthweight; 2 of these had asymmetry and were clearly identic...

To cite: Ricks CB, Grandhi R, Ducruet AF. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014207486 DESCRIPTION A 74-year-old woman with Klippel-Trenaunay syndrome (KTS) presented to the emergency room with 3 days of right arm and leg ataxia, gait instability, dysphagia and intermittent occipital headaches. Her physical examination was notable for left upper and ...