Neuroradiological, neurological, and neuropsychological studies before and after hemispherectomy for seizures of a six year old boy with left hemiplegia at birth revealed striking postoperative improvement. Seizures ceased and have not recurred. Preoperative EEC studies from seven months of age revealed increasing pathological involvement of the left as well as right hemisphere. Postoperatively...

Case Alex, with Sturge-Weber Syndrome affecting the left hemisphere, failed to develop speech throughout early boyhood, and his comprehension of single words and simple commands remained stagnant at an age equivalent of 3-4 years. But then, following left hemidecortication at age 8.5 years and withdrawal of anticonvulsants when he was more than 9 years old, Alex suddenly began to acquire speech...

The quantitative analysis of the smooth pursuit eye movements in a patient who had a left hemi­ spherectomy 11 years previously showed that although the remaining right hemisphere could generate normal pursuit to the right, leftward pur­ suit was always slower than the target velocity and requlred corrective saccades. The number of saccades was greatest at lower target speeds and decreased at h...

We investigated the clinical features and surgical outcome of 17 patients with refractory epilepsy secondary to CNS infection who were referred to a tertiary center for presurgical evaluation. Six patients had a history of meningitis and 11 patients had a history of encephalitis. Median age at infection was three years (40 days-40 years). Time to seizure onset was shorter in the encephalitis gr...

There has been a considerable increase in interest in the surgical management of intractable epilepsy in children. Better methods of diagnosis and improved knowledge of natural history and results of surgery have been major factors in this phenomenon. The results of surgery in 76 patients who were 19 years of age or younger are reported. Success rates, defined as no postoperative seizures with ...

Introduction Hemispherectomy is a last resort treatment for children with catastrophic hemispheric epilepsy. It abolishes seizures and improves quality of life. The remarkable motor recovery after hemispherectomy, observed in both clinical and experimental settings, reflects the plastic capacities of the brain, especially at young age. Direct cortical stimulation of the healthy hemisphere in ad...

In a child with left hemimegalencephaly and seizures, a reversible operculum syndrome developed when continuous epileptic discharges spread from the left hemisphere to the contralateral central regions. The operculum syndrome lasted for three months until left hemispherectomy was performed. Soon after surgery the seizures and the operculum syndrome resolved. The operculum syndrome is a facio-ph...