High trait anger is linked to adverse cardiovascular outcomes. A potential antidote to the cardiotoxic influence of anger is trait forgiveness (TF), as it has shown associations with improved blood pressure (BP) and cardiovagal tone regulation in cardiac patients. However, it has yet to be determined if anger and forgiveness independently predict cardiovascular parameters. Trait anger (State-Tr...

It has been well recognized that the nonlinear hemodynamic responses of the blood oxygenation level-dependent (BOLD) functional MRI (fMRI) are important and ubiquitous in a series of experimental paradigms, especially for the event-related fMRI. Although this phenomenon has been intensively studied and it has been found that the post-capillary venous expansion is an intrinsically nonlinear mech...

The aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18%) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2 : 1 ratio. The cardiac ou...

OBJECTIVE To develop an isolated working heart model with parabiotic circulation in swine and verify its stability and possibility to allow effective measurements of hemodynamic and metabolic data. METHODS This model was developed during study of association of agents to cardiology. There were performed 18 experiments, each with a support animal and a donor animal. Donor animal heart was perf...

Evaluating the systolic function of the left ventricle (LV) is important in the hemodynamic management of the critically ill patients with circulatory failure. Echocardiography is considered the standard monitor for estimating the LV function at the bedside in the intensive care unit. However, it requires a trained operator and is not a real-time monitoring tool. For monitoring of the systolic ...

PCG signal pattern classification, also known as auscultation pattern recognition, was one of the efficient computer-based methods applied to medical decision making. PCG Pattern recognition generally is interpreted in two ways. The most general definition includes recognition of patterns in any type of PCG dataset and is called uniform PCG pattern classification this discriminate peaks of hear...

Hemodynamic measurements were recorded every 30 minutes in 4 (porcine model) trials of 4 hours. Animals received a 0.5mg/kg endotoxin infusion over the first 30 minutes and underwent zero-balance continuous veno-venous filtration with 0.7m large pore substrate (80kDa cut-off) from 60 minutes onwards [1]. Subject-specific CVS models were fitted to 34 sets of data from the four trials. Each data ...

PRIMARY pulmonary hypertension (PPH) is an uncommon, almost uniformly fatal disease that generally affects young adults. The risk of death is best correlated with right ventricular hemodynamic indices and New York Heart Association functional class. Although anticoagulants, calcium-channel blockers and prostacyclin have shown great promise, lung transplantation remains the only viable treatment...

Introduction: Almost all studies on dynamic contrast-enhanced MRI (DCE-MRI) in the spine [1,2] are based on descriptive perfusion indices like maximum signal enhancement. These suffer from well-known limitations like dependence on experimental variables and an ill-defined relation to hemodynamic parameters. Quantitative analysis with the Tofts model resolves the first issue, but not the second ...