Submit Manuscript | http://medcraveonline.com Abbreviations: HBV: Hepatitis B Virus; HBs Ag: Hepatitis B Surface Antigen; HBe Ag: Hepatitis B e Antigen; anti-HBe Ab: Hepatitis B e Antibodies; HCC: Hepatocellular Carcinoma; HDV: Hepatits Delta Virus; GGT: Gamma-Glutamyl Transpeptidase; ALP: Alkaline Phosphatase; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; AFP: Alpha Foeto-Pro...

background occult hepatitis b virus infection (obi) is defined as the presence of hepatitis b virus (hbv) dna in the liver and/or in the serum of patients with negative results of hepatitis b s antigen (hbsag) test with or without serological markers of previous viral exposure. the impact of obi in patients with chronic hepatitis c (chc) is still unclear. objectives the aim of this study was to...

background hepatitis c virus (hcv) is the major cause of chronic liver disease. hcv is a single stranded positive sense rna of approximately 9.6 kb. because of high conservativeness of 5΄untranslated region of hcv genome, it is widely used for virus genotyping. different methods are used for the virus genotyping, but all involve some difficulties. objectives the aim of the present study was to ...

conclusions the comprehensive analysis of a protein with important roles has never been easy, and in case of e2 envelope glycoprotein of hgv, there is no much data on its molecular and immunological features, clinical significance and its pathogenic potential in hepatitis or any other gbv-c related diseases. so, results of the present study may explain some structural, physiological and immunol...

Hepatitis B virus splice-generated protein (HBSP), encoded by a spliced hepatitis B virus RNA, was recently identified in liver biopsy specimens from patients with chronic active hepatitis B. We investigated the possible generation of immunogenic peptides by the processing of this protein in vivo. We identified a panel of potential epitopes in HBSP by using predictive computational algorithms f...

OBJECTIVES The aims of this study are to investigate the prevalence of occult hepatitis B virus infection among patients with cryptogenic cirrhosis and to analyze the relationship between surface protein variability and occult hepatitis B virus infection, which may be related to the pathogenesis of occult hepatitis B virus infection in cryptogenic cirrhosis. Occult hepatitis B virus infection i...