نتایج جستجو برای: hepatocyte count
تعداد نتایج: 179874 فیلتر نتایج به سال:
"Hepatocyte hybridomas" have been isolated after fusion of adult hepatocytes and alpha-fetoprotein (AFP)-producing mouse hepatoma cells. The yield of viable hybrid clones was low but could be increased by culturing the cells in the presence of insulin. On the basis of their chromosome constitution, the hybrids were classified into two groups characterized by either a single or a double set of m...
Differentiation of adult bone marrow stem cells (BMSC) into hepatocyte-like cells is commonly performed by continuous exposure to a cytokines-cocktail. Here, it is shown that the differentiation efficacy in vitro can be considerably enhanced by sequential addition of liver-specific factors (fibroblast growth factor-4, hepatocyte growth factor, insulin-transferrin-sodium selenite, and dexamethas...
Guo, Hongtao, Junping Wei, Yusuke Inoue, Frank J. Gonzalez, and Paul C. Kuo. Serine/threonine phosphorylation regulates HNF-4 -dependent redox-mediated iNOS expression in hepatocytes. Am J Physiol Cell Physiol 284: C1090–C1099, 2003. First published December 4, 2002; 10.1152/ajpcell.00394.2002.—Nitric oxide (NO), endogenously synthesized by inducible NO synthase (iNOS), serves antioxidant and a...
BACKGROUND Sirtuin (Sirt), a sensor of the cell metabolic state, regulates glucose and lipid metabolism. The aim of this study was to address whether rosiglitazone (RGZ) alters hepatic Sirt1 and whether Sirt1 and/or Sirt6 have a regulatory role in the protective effects of RGZ on hepatocyte steatosis. METHODS To investigate the effect of RGZ on hepatic Sirt1, rats were administered with RGZ f...
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