BACKGROUND Erythrasma is a benign dermatosis that typically occurs on intertriginous skin. PURPOSE We describe a series of nine men with erythrasma that were successfully treated with mupirocin 2% ointment monotherapy. METHODS AND MATERIALS We reviewed PubMed for the following terms: erythrasma, mupirocin, ointment, treatment. We also reviewed papers containing these terms and their referen...

In developing of ointment for topical treatment of colds the structural and mechanical properties of the ointment bases contained isopropyl palmitate, beeswax and solid fat in different concentrations have been studied. Amount of isopropyl palmitate 60% remained constant and the ratio of solid fat and bee wax was varied. In order to study thixotropic properties the curve of kinetics deformation...

In the Present study, methanolic, chloroform and diethyl ether extracts of Adhatoda vasica Plants were evaluated for its wound healing activity in the form of Ointment dosage form in excision wound model in albino rats. The methanolic extract ointment of Adhatoda vasica showed a significant effect in excision wound model as comparable to standard drug and other two extracts of ointment, by calc...

BACKGROUND An aerosol foam formulation of fixed combination calcipotriene 0.005% (as hydrate; Cal) plus betamethasone dipropionate 0.064% (BD) was developed to improve psoriasis treatment. OBJECTIVES To compare the efficacy and safety of Cal/BD aerosol foam with Cal/BD ointment after 4 weeks. METHODS In this Phase II, multicenter, investigator-blind, 4-week trial, adult patients with psoria...

Salicylic acid was applied topically to the skin of rabbits and humans in order to study the pharmacokinetics of percutaneous absorption, and the effects of formulation and application variables on the rate and extent of absorption. Drug samples incorporated into hydrophilic ointment (USP} and hydrophilic ointment containing 10% urea, were applied to the shaved abdominal areas of female New Zea...

BACKGROUND Psoriasis vulgaris (PV) has been causing increasing concern due to its highly prevalent, harmful and therapy-resistant characteristics. The YXBCM01 (Chinese herbal medicine) for PV trial evaluates the effects of YXBCM01 on relapse rate in patients suffering from PV. As an update to the published design and method for the trial, this paper presents the statistical plan for the main pu...