Herpes are a group of similar viruses that responsible for number infecting diseases, the most important which herpes simplex, zoster and pseudopox. Resistance to traditional antiviral medications is becoming increasingly common, making treatment such infections even more difficult. For example, usage nucleoside analogues like acyclovir target DNA-polymerase virus on regular long-term basis pro...

background: the present study sought to investigate molecular evidence for association between the presence of herpes simplex virus (hsv), cytomegalovirus (cmv), and epstein-barr virus (ebv) in crc and colorectal polyp by using the pcr method in iran. methods: in this analytical case-control study, we selected 15 patients with crc, 20 patients with colorectal polyp, and 35 patients without mali...

OBJECTIVES Demonstrate that DNA viremia is common in pediatric sepsis and quantitate its associations with host immune function and secondary infection risk. DESIGN Retrospective analysis of a prospective cohort study. PATIENTS Seventy-three children admitted with sepsis-induced organ failure. INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS This study was performed as an ancillary inv...

OBJECTIVE To investigate the association between cerebral palsy and direct evidence for perinatal exposure to neurotropic viruses. DESIGN Population based case-control study. SETTING Adelaide Women's and Children's Hospital Research Laboratory. PARTICIPANTS AND MAIN OUTCOME MEASURES Newborn screening cards of 443 white case patients with cerebral palsy and 883 white controls were tested f...

Histiocytic necrotizing lymphadenitis (HNL) or Kikuchi's disease is a distinctive, self-limited disorder characterized by necrotizing cervical lymphadenopathy in young individuals. HNL is more prevalent among Asians and is a relatively common disorder among Koreans. A preceding fever, lymphopenia, and occasional skin rashes suggest a viral etiology and there have been sporadic reports of viral ...

herpes simplex virus (hsv) is one of the common pathogenic viruses of humans bing. this study aimed to determin anti-herpes virus activity of mentha piperita extracts in vitro. mentha piperita extracts can inhibit hsv infection when the cells treated before viral adsorbtion. hsv-1 were also inhibited by menthol after viral adsorption. hsv-1 viral particles were directly inhibited and viral yiel...

PURPOSE We looked for herpes simplex virus types 1 and 2 (HSV-1 and HSV-2, respectively), varicella zoster virus (VZV), Epstein-Barr virus (EBV) and cytomegalovirus (CMV) DNA in Malawian adults with clinically suspected meningitis. METHODS We collected cerebrospinal fluid (CSF) from consecutive adults admitted with clinically suspected meningitis to Queen Elizabeth Central Hospital (QECH), Bl...

BACKGROUND Virus isolation in cell culture is the recognised diagnostic gold standard for genital herpes. Although increasing evidence indicates that polymerase chain reaction (PCR) provides a more rapid and sensitive diagnostic method, its implementation in routine diagnostic settings has been limited by concerns over contamination and cost. OBJECTIVE To evaluate the feasibility of replacing...

INTRODUCTION Herpes simplex virus encephalitis (HSE) is an acute infection accompanied by significant morbidity and mortality with the diagnosis often made by cerebrospinal fluid (CSF) polymerase chain reaction (PCR) testing. CASE PRESENTATION We report a case of a healthy 35-year-old woman presenting with altered mental status. Due to suspicion of herpes encephalitis, a CSF PCR for herpes vi...

AIM To evaluate the diagnostic value of polymerase chain reaction (PCR) performed on aqueous humour for the detection of viral DNA in patients with necrotising herpetic retinitis. METHODS The clinical features and laboratory results of 22 patients (29 eyes) presenting with necrotising herpetic retinitis between March 1999 and June 2001 were reviewed retrospectively. Aqueous humour was obtaine...