TOPIC The role of the zoster vaccine in the prevention of herpes zoster and its sequelae, including postherpetic neuralgia (PHN) and herpes zoster ophthalmicus. CLINICAL RELEVANCE Wide administration of the herpes zoster vaccine in accordance with the recommendations of the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices (ACIP) will lead to a decline in...

Herpes zoster, as we all know, is produced by the Varicella-Zoster Virus and appears after reactivation of virus due to a situation immunosuppression, either an illness or 60 years age, related phenomenon immunosenescence, This happens when that person has suffered primary infection produces chickenpox, given subsequently, this capacity remain in dorsal ganglia spinal cord cranial pairs for lon...

The Varicella Zoster virus persists in sensory nerve ganglion cells after chicken pox and gets reactivated to cause herpes zoster after variable periods of time as a result of waning of specific cellular immunity. Susceptible contacts of herpes zoster can develop chicken pox and very rarely herpes zoster. We report an interesting case of a father and his son who developed herpes zoster simultan...

Herpes zoster is uncommon in immunocompetent children. The bilateral symmetrical occurrence of herpes zoster lesions is extremely rare. We report a 15-year-old immunocompetent Chinese adolescent boy who developed bilateral symmetrical herpes zoster lesions. To our knowledge, the occurrence of bilateral symmetrical herpes zoster lesions in an immunocompetent individual has not been reported in t...

BACKGROUND Whether the risk of cancer is increased among patients with herpes zoster is unclear. We investigated the risk of cancer among patients with herpes zoster using a nationwide health registry in Taiwan. METHODS We identified 35 871 patients with newly diagnosed herpes zoster during 2000-2008 from the National Health Insurance Research Database in Taiwan. We analyzed the standardized ...

The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster. This study aimed to investigate possible associations among natural killer cells, T cells and psychological stress in herpes zoster. Interfer...

BACKGROUND The incidence and severity of herpes zoster and postherpetic neuralgia increase with age in association with a progressive decline in cell-mediated immunity to varicella-zoster virus (VZV). We tested the hypothesis that vaccination against VZV would decrease the incidence, severity, or both of herpes zoster and postherpetic neuralgia among older adults. METHODS We enrolled 38,546 a...

Herpes zoster (shingles), a painful and disabling disease, affects an estimated 1 million individuals in the United States annually and results in significant morbidity, lost productivity, and diminished quality of life. Herpes zoster constitutes the reactivation of varicella-zoster virus (VZV), the same virus that causes chickenpox. After resolution of chickenpox, VZV remains dormant in dorsal...

The Varicella Zoster virus, analpha virus can present in two distinct forms. The primary infection, chicken pox or varicella, is a contagious but usually benign illness that occurs in epidemics among the susceptible children. After the initial infection, the virus remains dormant until there is a reactivation, leading to the secondary form of disease called Herpes Zoster. Herpes Zoster (HZ) is ...

Introduction: Varicella zoster virus is a highly infectious a-herpesvirus, pathogenic only to humans. The primary infection of varicella causes chickenpox, which contagious and primarily infects children adolescents in India. Following the infection, remains dormant sensory root ganglia. Activation later stages life herpes may vary from subclinical typical zoster, scattered vesicles, sine herpe...