Fingolimod is an oral, disease-modifying therapy used to treat multiple sclerosis (MS). However, severe viral infections, including disseminated varicella-zoster virus infection, herpes simplex encephalitis, varicella-zoster virus encephalitis and vasculopathy, or progressive multifocal leukoencephalopathy, have been reported during fingolimod therapy. Hemophagocytic lymphohistiocytosis (HLH), ...

Herpes zoster ophthalmicus (HZO) is a common, vision and potentially life-threatening disease caused by the reactivation of the varicella-zoster virus (VZV) in the distribution of the first division of cranial nerve V. Although the rate of herpes zoster increases with age, over half of the people with zoster in general, including HZO, are under age 60. In addition, over 90% of people with zoste...

The influence of herpes zoster virus infection on cell-mediated and humoral immunity to varicella-zoster virus (VZV), cytomegalovirus, and herpes simplex virus (HSV) was followed in 17 zoster patients from the first week to 6 months after start of eruptions. The clinical responses were registered and correlated to the immune responses. A significant depression in blast transformation on stimula...

Herpes zoster (HZ), or shingles, is a viral disease caused by the reactivation of varicella-zoster virus (VZV). While typically associated with aging, immunosuppression, stress, this case report presents an unusual trigger: exposure to hot water. A 76-year-old woman developed HZ localized trigeminal nerve dermatome following accidental The patient was successfully treated acyclovir, symptoms re...

BACKGROUND Herpes zoster is a common viral infection of skin caused by reactivation of varicella zoster virus infection from the spinal ganglia. The clinico-epidemiological patterns of this disease in an Indian setting required to be studied. METHODS A cross sectional study was conducted on all consecutive cases of herpes zoster reporting to the Dermatology Outpatient Department at a Tertiary...

Submit Manuscript | http://medcraveonline.com Abbreviations: ACE: Alternative Cellular Energy; HIV: Human Immunodeficiency Virus; HSV: Herpes Simplex Virus; HZV: Herpes Zoster Virus; HPV: Human Papillomaviruses; KELEA: Kinetic Energy Limiting Electrostatic Attraction; SCMV: African Green Monkey Simian Cytomegalovirus; CPE: Cytopathic Effect; CTL: Cytotoxic T Lymphocytes; CAM: Complementary and ...

1. Chandra PC, Patel H, Schiavello HJ, Briggs SL. Successful pregnancy outcome after complicated varicella pneumonia. Obstet Gynecol 1998;92:680-682. 2. Dahl H, Marcoccia J, Linde A. Antigen detection: the method of choice in comparison with virus isolation and serology for laboratory diagnosis of herpes zoster in human immunodeficiency virus-infected patients. J Clin Microbiol 1997;35:347-349....

Submit Manuscript | http://medcraveonline.com Abbreviations: KELEA: Kinetic Energy Limiting Electrostatic Attraction; ACE: Alternative Cellular Energy; ICE: Insufficiency of Cellular Energy; AIDS: Acquired Immunodeficiency Syndrome; CFS: Chronic Fatigue Syndrome; HSV: Herpes Simplex Virus; HZV: Herpes Zoster Virus; HPV: Human Papillomavirus; HIV: Human Immunodeficiency Virus; UV: Ultraviolet; S...

Herpes simplex virus (HSV) and varicella-zoster virus (VZV) are both human alpha-herpes viruses. They are capable of establishing latent infections in neural tissues and to reactive from these sites, determining the clinical features of the disease (primary infection versus recurrences). Infections with these viruses are common; an increased number of elderly and immunocompromised individuals w...

BACKGROUND Herpes zoster or, as it is commonly called, 'shingles' is a neurocutaneous disease characterised by the reactivation of varicella zoster virus (VZV), the virus that causes chickenpox, which is latent in the dorsal spinal ganglia when immunity to VZV declines. It is an extremely painful condition which can often last for many weeks or months, impairing the patient's quality of life. T...