نتایج جستجو برای: hexosaminidase b
تعداد نتایج: 899988 فیلتر نتایج به سال:
In the assay for hexosaminidase A (Hex A) in leukocytes, cultured fibroblasts, and cultured amniotic fluid cells for the detection of Tay-Sachs disease and carrier identification, bovine serum albumin (BSA) is used (1,2). We find that some BSA preparations are contaminated with hexosaminidase activity. We wish to warn others of this and to show how an incorrect diagnosis could be reached by usi...
Because thrombin-induced inflammation is partially mast cell-dependent and involves proteinase-activated receptors (PARs), we hypothesized that mast cells express PAR and can be stimulated with PAR-activating peptides (PAR-AP). We demonstrated that rat peritoneal mast cells expressed PAR-1 and PAR-2 mRNA, and that PAR-2AP (tc-LIGRLO-NH(2), 1 microm) induced 64.2 +/- 4.4% specific beta-hexosamin...
BACKGROUND AND OBJECTIVE Platelet-activating factor (PAF) is a lipid mediator involved in the pathophysiology of several allergic diseases, for example, in the amplification of mast cell (MC) activation in anaphylaxis. Rupatadine is an antihistamine with a demonstrated anti-PAF effect, although its capacity to inhibit PAF-induced MC degranulation has not been fully evaluated. Objectives: To comp...
Stimulation of lacrimal acini with secretagogues such as carbachol initiates movement and fusion of acinar secretory vesicles with the apical plasma membrane, resulting in release of protein into the nascent tear fluid. Using rabbit lacrimal acini reconstituted in vitro from isolated cells, we have investigated the organization of the apical cytoskeleton and its role in stimulated secretion. Co...
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