Micellization of the ionic surfactant sodium hexyl sulfate has been studied using atomistic explicit-solvent molecular dynamics simulations with and without excess NaCl or CaCl(2). Simulations were performed at surfactant loadings near the critical micellization concentration. Equilibrium micelle size distributions and estimates of the critical micellization concentration obtained from the simu...

Background An HPLC method employing a post-column derivatization strategy using the cupric reducing antioxidant capacity reagent (CUPRAC reagent) for the determining antioxidants in plant-based materials leverages the separation capability of regular HPLC approaches while allowing for detection specificity for antioxidants. Methods Three different column types, namely core-shell and porous si...

Sophorolipids (SLs), produced by Candida bombicola, are of interest as potential replacements for hazardous commercial surfactants. For the first time, a series of molecularly edited SLs with ethyl (EE), n-hexyl (HE), and n-decyl (DE) esters were evaluated at an oil (almond oil)-water interface for their ability to reduce interfacial tension (IFT) and generate stable emulsions. An increase in t...

This experiment was conducted with the objective of evaluating the performance sage (Salvia officinalis L.) in different agroecology of Ethiopia for morpho-agronomic and chemical traits at Wondo genet, Hawassa, Qoqa and Holleta for two years from 2011/2012 to 2012/2013 cropping seasons. Data on plant height, branch number/plant, fresh leaf weight/plant, fresh stem weight/plant, above ground bio...

A new synthetic route to mechanochemically produce silicon nanoparticles modified with biocompatible and chromophoric molecular compounds using the Williamson ether synthesis is described. This reaction allows a direct grafting of organic compounds such as phenol, hydroquinone and tetraethylene glycol to the silicon nanoparticle surface in an efficient fashion. Specifically, the formation of (p...

Chiral macrocycles with eight (R)- and (S)-methylbenzylurea residues on the resorcinarene skeleton linked through a hexyl or dodecyl spacer having amide linkages have been prepared by the reactions of the corresponding octaamine derivative with (R)- and (S)-alpha-methylbenzylisocyanate, respectively. In chloroform, the urea-functionalized resorcinarenes with hexyl spacers form intramolecular hy...

To gain information about the properties of tyrosyl residues buried within proteins, the circular dichroism (CD) and absorption spectra of tyrosine derivatives have been investigated in nonpolar solvents. N-Stearyl-L-tyrosine n-hexyl ester dissolved in methylcyclohexane (O-O band at 283 nm) was used to measure the effects of hydrogen-bonding agents. Adding low concentrations of dioxane, N, N-di...

The naturally occurring compound 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) was isolated from Wasabia japonica (Wasabi), a pungent spice used in Japanese food worldwide. The synthetic derivatives 6-(methylsulfenyl)hexyl isothiocyanate (I7447) and 6-(methylsulfonyl)hexyl isothiocyanate (I7557) are small molecule compounds derived from 6-MITC. This study aimed to evaluate the effect of these...

To gain information about the properties of tyrosyl residues buried within proteins, the circular dichroism (CD) and absorption spectra of tyrosine derivatives have been investigated in nonpolar solvents. N-Stearyl-L-tyrosine n-hexyl ester dissolved in methylcyclohexane (O-O band at 283 nm) was used to measure the effects of hydrogen-bonding agents. Adding low concentrations of dioxane, N, N-di...

Ceramide is an important constituent of stratum corneum lipids, which act as both physical barriers and signal modulators. We synthesized several ceramide derivatives and investigated their effects on keratinocyte differentiation. RT-PCR and Western blotting showed that the novel synthetic ceramide derivatives K6PC-4 [N-(2,3-dihydroxypropyl)-2-hexyl-3-oxo-decanamide], K6PC-5, [N-(1,3-dihydroxyp...