Previous studies have reported that high fat feeding in mild to moderate heart failure (HF) results in the preservation of contractile function. Recent evidence has suggested that preventing the switch from fatty acid to glucose metabolism in HF may ameliorate dysfunction, and insulin resistance is one potential mechanism for regulating substrate utilization. This study was designed to determin...

BACKGROUND Anaemia is common among patients with heart failure (HF) and is an important prognostic marker. AIM We sought to determine the prognostic importance of anaemia in a large multinational pooled dataset of prospectively enrolled HF patients, with the specific aim to determine the prognostic role of anaemia in HF with preserved and reduced ejection fraction (HF-PEF and HF-REF, respecti...

BACKGROUND Hippocampal formation (HF) volume and episodic memory performance are substantially heritable, but HF subregion heritability estimates and their possible shared genetic variance with episodic memory performance remain to be determined. METHODS AND FINDINGS This study provides heritability estimates for hippocampal subregions (e.g, Cornu Amonis, Subiculum, Parasubiculum, Molecular a...

BACKGROUND Heart failure with preserved ejection fraction (EF) is a common syndrome, but trends in treatments and outcomes are lacking. METHODS AND RESULTS We analyzed data from 275 hospitals in Get With the Guidelines-Heart Failure from January 2005 to October 2010. Patients were stratified by EF as reduced EF (EF <40% [HF-reduced EF]), borderline EF (40%≤EF<50% [HF-borderline EF]), or prese...

BACKGROUD/OBEJECTIVES This study aims to find out the effects of peanut sprout extracts on weight controls and protein expressions of transcription factors related to adipocyte differentiation and adipocytokine in rats under high-fat diets. MATERIALS/METHODS Four week-old Sparague-Dawley (SD) were assigned to 4 groups; normal-fat (NF) diets (7% fat diet), high-fat (HF) diets (20% fat diet), h...

Background Heart failure (HF) is a pathological condition during which the pump function of the heart is compromised. There are two major forms: diastolic and systolic HF. Whilst the majority of patients exhibit systolic HF (reduced ejection fraction), diastolic HF (normal ejection fraction) has also been found in almost half of HF patients. A major question in this field is the inter-relations...

Harris Corporation has an interest in making HF radios a suitable medium for wireless information networks using standard Internet protocols. Although HF radio links have many unique characteristics, HF wireless subnets can be subject to many of the same traffic flow characteristics and topologies as existing line-of-sight (LOS) radio networks, giving rise to similar issues (media access, conne...

Chronic heart failure (HF) is a leading clinical and public problem posing a higher risk of morbidity and mortality in different populations. HF appears to be in both phenotypic forms: HF with reduced left ventricular ejection fraction (HFrEF) and HF with preserved left ventricular ejection fraction (HFpEF). Although both HF phenotypes can be distinguished through clinical features, co-morbidit...

OBJECTIVE We determined the potential programming effects of maternal obesity and high-fat (HF) diet during pregnancy and/or lactation on offspring metabolic syndrome. STUDY DESIGN A rat model of maternal obesity was created using an HF diet prior to and throughout pregnancy and lactation. At birth, pups were cross-fostered, thereby generating 4 paradigms of maternal diets during pregnancy/la...

OBJECTIVES This study sought to describe the occurrence and timing of heart failure (HF), associated clinical factors, and 30-day outcomes in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS). BACKGROUND Little is known about HF-complicating NSTE-ACS. METHODS Using pooled patient-level data from 7 clinical trials from 1994 to 2008, we describe the occurrence and tim...