نتایج جستجو برای: hi gene
تعداد نتایج: 1154693 فیلتر نتایج به سال:
we have measured the competitive antagonistic effect of chlorpheniramine in bronchi of 8 normal and 12 asthmatic subjects. classical pharmacological theory states that the degree of competitive antagonism depends only upon 1) antagonist concentration at the receptor, and 2) receptor affinity. delivery and affinity also influence agonist responsiveness, but measurement of bronchial antagonism al...
Polr(A) pBCO is designed for assaying promoter activity of sequences cloned upstream of the CAT gene, and was obtained by cloning a Bam HI Hind III fragment from pSVOCAT into the Bam HI and Hind III sites of Bluescript KS+. Plasmids pBCTKp-1 and -2, and pBCSVp-1 and -2 are designed for assaying enhancer or silencer activity, and were obtained by cloning the fragments indicated from pMSV.TK.CAT ...
Postnatal mammary gland development and differentiation occur during puberty and pregnancy. To explore the role of DNA methylation in these processes, we determined the genome-wide DNA methylation and gene expression profiles of CD24(+)CD61(+)CD29(hi), CD24(+)CD61(+)CD29(lo), and CD24(+)CD61(-)CD29(lo) cell populations that were previously associated with distinct biological properties at diffe...
Harlequin ichthyosis (HI) is a rare autosomal recessive congenital with an incidence of 1 in 300,000 live births. It lethal 44% cases and the baby usually prematurely born. These babies have thick, highly keratinized armor-like skin, which forms large diamond, trapezoid or rectangular plates separated by deep fissures. affect shapes eyelids, nose, mouth ears, also limit movement arms, legs ches...
Haploids and doubled haploids are invaluable for basic genetic studies and in crop improvement. A novel method of haploid induction through genetic engineering of the Centromere Histone Protein gene, CENH3, has been demonstrated in Arabidopsis. The present study was undertaken to develop haploid inducer (HI) lines of Brassica juncea based on the principles elaborated in Arabidopsis. B. juncea w...
Mice expressing a Cre recombinase from the lysozyme M-encoding locus (Lyz2) have been widely used to dissect gene function in macrophages and neutrophils. Here, we show that while naïve resident tissue macrophages from IL-4Rαf(lox/delta)LysM(Cre) mice almost completely lose IL-4Rα function, a large fraction of macrophages elicited by sterile inflammatory stimuli, Schistosoma mansoni eggs, or S....
The spatial organization of the genome plays a crucial role in the regulation of gene expression. Recent experimental techniques like Hi-C have emphasized the segmentation of genomes into interaction compartments that constitute conserved functional domains participating in the maintenance of a proper cell identity. Here, we propose a novel method, IC-Finder, to identify interaction compartment...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید