CASE REPORT. A 46year old man presented with a three month history of hiccup, occurring almost daily but associated only with the swallowing of solid food. It usually settled with a glass of water, the longest attack lasting almost thirty minutes. Indeed, it was this attack which precipitated his referral. On careful questioning at the time and retrospectively, he denied any dysphagia whatsoeve...

Our case involves persistent hiccup arising in an adolescent with obsessive compulsive disorder (OCD) who was using aripiprazole as an augmentation to fluoxetine and whose hiccups remitted with dose reduction and rechallenge. Treatment suggested that aripiprazole might lead to hiccups. Antipsychotics are also used for the treatment of hiccups, but recent case reports suggest that they cause hic...

Hiccups, or singulata (hiccup is singultus), are commonly experienced by most people at one time or another and are usually brief and self-limiting. Although pharmacotherapeutic agents are not generally considered causal in the etiology of hiccups, many clinicians empirically associate episodic hiccups in their patients as being drug induced. The two classes of drugs most often cited as causing...

A 21-year-old right-handed man developed progressive dysarthria and gait disturbance over 4 months (associated with intermittent hiccups). During that time, he also suffered from uveitis. A physical examination showed pseudobulbar and pyramidal signs and genital and oral ulcers. A brain MRI revealed an extensive lesion mainly located in the ventral pons, with an extension upwards to the midbrai...

OBJECTIVE The objective of this study was to investigate the effects of acupuncture treatment for persistent hiccups in cancer patients. DESIGN The study design was a retrospective case series. SETTINGS/LOCATION The study setting was the Clinical Research Center of the National Institutes of Health. SUBJECTS The subjects were 16 adult male patients ages 27-71 with cancer, with persistent ...

BACKGROUND Hiccups are an infrequent result of lateral medullary infarction. Their importance may be underestimated and they can cause distress, exhaustion, and aspiration. Hiccups in lateral medullary infarction remain poorly understood OBJECTIVE To evaluate the relation between the lesional loci of lateral medullary infarction and hiccups. METHODS 51 patients with lateral medullary infarc...