نتایج جستجو برای: high functional autism
تعداد نتایج: 2581550 فیلتر نتایج به سال:
Although widespread alterations in cortical structure have been documented in individuals with autism, the functional implications of these alterations remain to be determined. Here, we adopted a novel inter-subject correlation (inter-SC) and intra-subject correlation (intra-SC) technique to quantify the reliability of the spatio-temporal responses of functional MR activity in adults with autis...
Since involved in synaptic transmission and located on X-chromosome, neuroligins 3 and 4X have been studied as good positional and functional candidate genes for autism spectrum disorder pathogenesis, although contradictory results have been reported. Here, we performed a case-control study to assess the association between noncoding genetic variants in NLGN3 and NLGN4X genes and autism, in an ...
Infantile autism is a pervasive developmental disorder with a strong genetic component. The mode of inheritance appears to be complex and no specific susceptibility genes have yet been identified. Chromosome 16p13.3 may contain a susceptibility gene based on findings from genome scans and reports of chromosome abnormalities in individuals with autism. The somatostatin receptor 5 (SSTR5) gene is...
Although the neurobiological understanding of autism has been increasing exponentially, the diagnosis of autism spectrum conditions still rests entirely on behavioral criteria. Autism is therefore most productively approached using a combination of biological and psychological theory. The triad of behavioral abnormalities in social function, communication, and restricted and repetitive behavior...
Background & Aims: Autism spectrum disorder is neurodevelopmental disorder characterized by social-communication difficulties and stereotyped behaviors. The present study evaluates the effects of cognitive rehabilitation based on inverse imitation on recognition of basic emotion in children with high functioning autism disorder. Materials Method: The method was quasi-experimental and single-...
Recently, carriers of a common variant in the autism risk gene, CNTNAP2, were found to have altered functional brain connectivity using functional MRI. Here, we scanned 328 young adults with high-field (4-Tesla) diffusion imaging, to test the hypothesis that carriers of this gene variant would have altered structural brain connectivity. All participants (209 women, 119 men, age: 23.4±2.17 SD ye...
Individuals with autism spectrum disorder (ASD) are found to have difficulties in understanding speech adverse conditions. In this study, we used noise-vocoded (VS) investigate neural processing of degraded individuals ASD. We ran fMRI experiments the ASD group and a typically developed control (TDC) while they listened clear (CS), VS, spectrally rotated VS (SRVS), were requested pay attention ...
In 2004, two papers proposed that pervasive functional under-connectivity (Just et al., ) or a trade-off between excessive local connectivity at the cost of distal under-connectivity (Belmonte et al., ) characterizes atypical brain organization in autism. Here, we take stock of the most recent and rigorous functional and structural connectivity findings with a careful eye toward evaluating the ...
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