نتایج جستجو برای: high risk genotypes
تعداد نتایج: 2801279 فیلتر نتایج به سال:
background:diabetic retinopathy (dr) is a sight-threatening microvascular complication of diabetes in which the vascular endothelium is damaged due to oxidative stress and inflammation, and vitreous vegf concentration becomes elevated. the aim of the present study was to assess the association of dr with genetic variations of the mnsod, a major antioxidant enzyme, and vegf, an important mediato...
the original biophysical profile is time consuming and costly. this study was performed to compare diagnostic value of the original fetal biophysical profile to the modified biophysical profile. patients were selected from high risk pregnancies referred for fetal assessment and were randomly assigned to two groups. the measures of outcomes were perinatal mortality, cesarean section for abnormal...
human immunodeficiency virus (hiv) is a public health challenge facing both developing and developed nations. although injecting drug use is even the main route of hiv transmission in iran, sexual route is rising gradually. vulnerable women have been considered as important bridging population for driving hiv epidemics. to increase the access to vulnerable women, in 2007, 5 pilot centers were e...
background & aim: the most important risk factor for one’s sexual health is high-risk sexual behavior. implementation of educational programs has been considered as one of the most crucial interventions in the prevention and treatment of these behaviors. therefore, this study aimed to determine the effect of an educational program on the knowledge and attitude of female sex workers toward prev...
conclusions our study revealed that patients with the diagnosis of breast cancer have greater bpe in comparison with control group. the results may be indicative for higher probability of developing breast cancer in patients with higher bpe. therefore, ce-mri could be a useful tool for breast cancer risk assessment. objectives background parenchymal enhancement (bpe) on contrast-enhanced magnet...
BACKGROUND The majority of human papillomavirus (HPV)-related oropharyngeal carcinomas (OPCs) are associated with HPV genotype 16; however, OPC can be associated with other high-risk non-HPV16 genotypes. METHODS This was a retrospective analysis of patients with high-risk non-HPV16 OPC treated at a single tertiary institution. Sociodemographic and clinical information was obtained by chart re...
glutathione s-transferases (gsts; ec: 2.5.1.18) are a ubiquitous family of eukaryotic and prokaryotic phase ii metabolic isozymes. genes encoding gstm1 (omim: 138350), and gstt1 (omim: 600436) are members of class mu and theta, respectively. the most common polymorphism in the gstm1 is a deletion of the whole gstm1 gene with a lack of enzyme activity. a homozygous deletion in the gstt1 has also...
BACKGROUND Curaçao is a Dutch-Caribbean Island located in a high-risk area for cervical cancer.Prior to introduction of a prophylactic human papillomavirus (HPV) vaccine, knowledge of the prevalence of high-risk HPV vaccine genotypes (HPV16, 18, 31, 33, 45, 52 and 58) in cervical (pre)cancer is required. OBJECTIVE To investigate the prevalence of HPV genotypes in invasive cervical cancers (IC...
objective(s): to investigate the association of single nucleotide polymorphisms (snps) in the peroxisome proliferator-activated receptors gamma (pparg) with essential hypertension (eh) and additional role of gene– high-density lipoprotein cholesterol (hdl) interaction. materials and methods:a total of 1640 patients with eh (806 males, 834 females), with a mean age of 52.5±12.6 years, were selec...
Much interest has been drawn to possible associations between vitamin D receptor (VDR) gene polymorphisms and colorectal cancer risk in conjunction with potentially protective effects of calcium and vitamin D. In a study of 685 cases of colorectal cancer and 778 community controls in Japan, we examined the associations of the FokI, BsmI, ApaI, and TaqI polymorphisms with colorectal cancer risk ...
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