SYSTOLIC TIME INTERVALS (STI) have become one of the established "noninvasive" techniques of clinical cardiology. Indeed the term "noninvasive" was first used in connection with the STI. The STI were one of the first quantitative noninvasive tests of cardiac function and remain one of the simplest and most reliable to perform. Most tests of ventricular performance deal with force and/or distanc...

Interactions between the Bcr-Abl kinase inhibitor STI-571 (imatinib mesylate) and a novel microtubule-targeting agent (MTA), pyrrolo-1,5-benzoxazepine (PBOX)-6, were investigated in STI-571-sensitive and -resistant human chronic myeloid leukemia (CML) cells. Cotreatment of PBOX-6 with STI-571 induced significantly more apoptosis in Bcr-Abl-positive CML cell lines (K562 and LAMA-84) than either ...

It has been widely believed that, by combining the services for preventing and treating sexually transmitted infections (STI) with those for family planning (FP), STI coverage would increase and the combined service would be of higher quality and more responsive to the needs of women. So far, there is little concrete evidence that integration has had such an impact. Besides the absence of docum...

BACKGROUND Intimate partner violence (IPV) is common among young adult relationships, and is associated with significant morbidity, including sexually transmitted infections (STI). This study measured the association between IPV victimization and perpetration and prevalent STIs and STI-risk behaviors among a sample of young women. METHODS This analysis uses wave 3 of the National Longitudinal...

Significant numbers of adolescents are initiating sexual activity at age 17 and younger. Little is known about this younger population of adolescents. This includes risk or protective factors for sexual activity and sexually transmitted infection (STI) acquisition. To safeguard all adolescents from the consequences of risky sexual behaviors, and to insure age appropriate and effective intervent...

BACKGROUND In sub-Saharan Africa, female sex workers (FSWs) are a vulnerable high risk group for the acquisition and transmission of sexually transmitted infections (STI) and HIV. OBJECTIVES To study parameters of sexual behaviour and knowledge of STI and HIV, to describe health seeking behaviour related to STI, and to measure the prevalence of gonorrhoea, chlamydia, syphilis, and HIV-1, to p...

AIMS The study was designed to test the influence of the temporal resolution, at which tissue Doppler imaging (TDI) and speckle tracking imaging (STI) operate, on the accurate assessment of left ventricular (LV) untwist rate (UR). METHODS AND RESULTS Echo imaging and invasive LV pressure measurements were performed during right atrial (RA) pacing and dobutamine challenge in eight pigs. LV tor...

OBJECTIVE To identify risk factors for incident sexually transmitted infections (STI) in a remote Aboriginal community in Australia. DESIGN A population based cohort study. SETTING An Aboriginal community in central Australia. PARTICIPANTS 1034 Aboriginal people aged 12-40 years, resident in the study region, seen during the period 1 January 1996 to 30 June 1998 for STI diagnosis. MAIN ...

Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of patients accessing sexually transmitted infection (STI) care at the Baltimore City Health Departme...

An integral part of the IBM eServer z990 I/O subsystem is the self-timed interface (STI) switch chip. The STI switch is an application-specific integrated circuit (ASIC) designed to provide high I/O connectivity and high bandwidth within the system. The complexity of the functional verification of the STI switch chip is inherent in the implementation of seventeen logical clock domains and the s...