Liposome gels bearing an antineoplastic agent, 5-fluorouracil, intended for topical application have been prepared and drug release properties in vitro have been evaluated. Different formulations of liposomes were prepared by the film hydration method by varying the lipid phase composition (PL 90H/cholesterol mass ratio) and hydration conditions of dry lipid film (drug/aqueous phase mass ratio)...

In Music Emotion Research, the goal is to quantify and explain how music influences our emotional states. Scientists realize that human brain is relevant to emotion, and it leads to the study of human emotion by capturing information from brain. Electroencephalogram (EEG) is an efficient tool to capture brainwave. This research proposes a framework to recognize human emotions during music liste...

The use of nanoporous anodic alumina (NAA) for the development of drug delivery systems has gained much attention in recent years. The release of drugs loaded inside NAA pores is complex and depends on the morphology of the pores. In this study, NAA, with different three-dimensional (3D) pore structures (cylindrical pores with several pore diameters, multilayered nanofunnels, and multilayered i...

Drugs that have narrow absorption window in the gastro-intestinal tract (GIT) will have poor absorption. For these drugs, gastro-retentive drug delivery systems offer the advantages in prolonging the gastric emptying time. Floating and sustained release tablets are developed by using a combination of hydrophilic polymer (Hydroxypropyl methylcellulose) and effervescent substance (Sodium bicarbon...

The aim of this study is to develop a once-daily sustained release matrix tablet of ibuprofen using hydroxypropyl methylcellulose (HPMC) as release controlling factor and to evaluate drug release parameters as per various release kinetic models. In order to achieve required sustained release profile tablets were directly compressed using Avicel pH 101 and Magnesium stearate. The formulated tabl...

Aceclofenac was formulated as novel enteric microcapsules for improved delivery to the intestine using the polymer ethyl cellulose as the retardant material. Micro encapsulation of aceclofenac was done to achieve a controlled drug release profile suitable for per oral administration. Aceclofenac was used as core and microcapsules were prepared by an emulsion solvent evaporation method. The prep...

Abstract More than one teramole of carbon per year is subducted as carbonate or carbonaceous material. However, the influence carbonation/decarbonation reactions on seismic activity within subduction zones poorly understood. Here we present field and microstructural observations, including stable isotope analyses, veins Higuchi serpentinite body, Japan. We find that oxygen compositions indicate...

There is a well known result from the Fierz-Pauli (FP) theory in de Sitter background that existence of lower bound for mass $m$ spin 2 particle, Higuchi bound. It establishes $m^2\geq 2H^2$, where $H$ Hubble parameter, order to presents no ghost-like instabilities. In this sense, should be unacceptable high fulfill condition at time inflationary epoch Universe, posing difficulty conciliate FP ...

Developing biomaterials for tissue regeneration is a promising alternative the recovery of various tissues, including bone. Atorvastatin (ATV) has series beneficial effects which includes bone anabolism, vasodilating, and anti-inflammatory actions. The main objective this work was to produce characterize polycaprolactone (PCL) matrices incorporated with ATV. Samples were prepared by solvent cas...

Release properties from a wax matrix tablet was examined. To obtain basic release properties, the wax matrix tablet was prepared from a physical mixture of drug and wax powder (hydrogenated caster oil) at a fixed mixing ratio. Properties of release from the single flat-faced surface or curved side surface of the wax matrix tablet were examined. The applicability of the square-root time law and ...