The aim of the present study was to determine the effect of the histaminergic precursor L-histidine and the H3 receptor antagonist thioperamide on the learning process of zebrafish submitted or not to confinement stress. On each of the 5 consecutive days of experiment (D1, D2, D3, D4, D5), animals had to associate an interruption of the aquarium air supply with food offering. Non-stressed zebra...

Since exogenous histamine has been previously shown to increase the somatostatin (SS) receptor-effector system in the rat frontoparietal cortex and both histamine H1-receptor agonists and SS modulate higher nervous activity and have anticonvulsive properties, it was of interest to determine the participation of the H1-histaminergic system in this response. The intracerebroventricular (i.c.v.) a...

1. Abstract 2. Introduction 3. Brainstem arousal systems 3.1. The reticular formation 3.2. The cholinergic ponto-mesencephalic neurons 3.3. The noradrenergic locus coeruleus neurons 3.4. The dopaminergic ventral mesencephalic neurons 3.5. The serotonergic raphe neurons 4. Thalamo-cortical activating system 5. Hypothalamic arousal systems 5.1. The posterior hypothalamus 5.2. The histaminergic tu...

This study investigated the effects of bilateral intraamygdalar microinjections of PNU-282987, a nicotinic cholinergic agonist, on anxiety and the reversal of amnesia induced by chlorpheniramine (CPA), an H1 histaminergic antagonist, in mice subjected to the elevated plusmaze (EPM). Two experiments were performed with seventy-nine adult male Swiss mice. The isolated microinjections of PNU-28298...

Involvement of Histaminergic Inputs in the Jaw-Closing Reflex Arc 1 2 Chikako Gemba,* Kiyomi Nakayama,* Shiro Nakamura, Ayako Mochizuki, Mitsuko 3 Inoue, Tomio Inoue 4 5 Department of Oral Physiology, Showa University School of Dentistry, Shinagawa-ku, Tokyo, 6 Japan; and Department of Pediatric Dentistry, Showa University School of Dentistry, 7 Oota-ku, Tokyo, Japan 8 9 Running head: HISTAMINE...

In a recent study, we examined the glycemic and autonomic nervous responses to probiotic strain Lactobacillus johnsonii La1, and presented evidence that intraduodenal (ID) injection of this bacteria affected autonomic nerves and lowered blood pressure (BP) in anesthetized rats. In the study presented here, we examined the feeding, autonomic and cardiovascular effects of the lactobacillus strain...