The GTPase ARL13B is localized to primary cilia; small cellular protrusions that act as antennae. Its defective ARL13B hennin (HNN) variant is linked causally with Joubert Syndrome, a developmental ciliopathy attributed to poor sensing of extracellular chemical gradients. We tested the hypothesis that impaired detection of extracellular voltage gradients also contributes to the HNN phenotype. I...

s For the on-line safe path planning of a mobile robot in unknown environments, the paper proposes a simple Hopfield Neural Network ( HNN ) planner. Without learning process, the HNN plans a safe path with consideration of “ too close” or “ too far” . For obstacles of arbitrary shape, we prove that the HNN has no unexpected local attractive point and can find a steepest climbing path, if a feas...

Several studies have linked cilia and Hedgehog signaling, but the precise roles of ciliary proteins in signal transduction remain enigmatic. Here we describe a mouse mutation, hennin (hnn), that causes coupled defects in cilia structure and Sonic hedgehog (Shh) signaling. The hnn mutant cilia are short with a specific defect in the structure of the ciliary axoneme, and the hnn neural tube shows...

This paper presents the locomotion control of a microelectromechanical system (MEMS) microrobot. The MEMS microrobot demonstrates locomotion control by pulse-type hardware neural networks (P-HNN). P-HNN generate oscillatory patterns of electrical activity like those of living organisms. The basic component of P-HNN is a pulse-type hardware neuron model (P-HNM). The P-HNM has the same basic feat...

Hexapod locomotive Micro-Electro Mechanical Systems (MEMS) microrobot with Pulse-type Hardware Neural Networks (P-HNN) locomotion controlling system is presented in this chapter. MEMS microrobot is less than 5 mm width, length, and height in size. MEMS microrobot is made from a silicon wafer fabricated by micro fabrication technology to realize the small size mechanical components. The mechanic...

In Orthogonal frequency division multiplexing (OFDM) transmission system, channel variations within an OFDM symbol destroy orthogonality between subcarriers, resulting in intercarrier interference (ICI), which increases an error floor in proportional to normalized Doppler frequency. To mitigate the effects of channel variations, in this paper, we propose a novel ICI suppression technique, which...

A famous theorem of P. Novikov 1955 and W. W. Boone 1959 asserts the existence of a finitely presented group with unsolvable word problem. In my Spring 2005 topics course (MATH 574, Topics in Mathematical Logic), I presented Boone’s proof, as simplified by J. L. Britton, 1963. In this seminar I shall present a truly slick, streamlined proof, due to S. Aanderaa and D. E. Cohen, 1980. Instead of ...

In this paper we prove several results regarding decidability ofthe membership problem for certain submonoids in amalgamated free prod-ucts and HNN extensions of groups. These general are then appliedto solve the prefix a number classes one-relatorgroups which low Magnus–Moldavanski i hierarchy. Since pre-fix one-relator groups is intimately related to theword special inverse monoids theE-unita...

* 0-7803-7952-7/03/$17.00 © 2003 IEEE. Abstract This paper presents a neural solution for clustering without pre-specifying the number of clusters. The presented clustering approach incorporates a harmonic neural network (HNN) and a codewordagglomerating neural network (ANN). The HNN harmonizes criteria of mean squared error and information entropy to exploit the substructure in the input data ...