This work deals with exploring some empirical scales of nucleophilicity. We have started evaluating the experimental indices of nucleophilicity proposed by Legon and Millen on the basis of the measure of the force constants derived from vibrational frequencies using a probe dipole H-X (X = F,CN). The correlation among some theoretical parameters with this experimental scale has been evaluated. ...

THE LEWIS blood group antigens Lea and Leb have been found on red blood cells (RBCs), in secretions and fluids such as saliva, alimentary tract juice, and urine, and in various tissues including renal tubular cells, collecting ducts, urothelium, and ductal or mucosal epithelium of the sweat glands, salivary glands, gastrointestinal tract, pancreas, uterus, cervix, and breast. l .s Hepatic bile ...

A recent study on the Holstein/Friesian (HOL) breed has indicated that the rapid rise in percentage Holstein genes in the United Kingdom (UK) has been accompanied by an increasing rate of inbreeding (Kearney et al., 2004). They reported an average inbreeding rate of 0.17% per year since 1992. Some of the consequences of inbreeding, for instance, inbreeding depression, are expected to be more pr...

One hundred and five cases of various human lung neoplasms were studied immunohistochemically using monoclonal antibodies recognizing the antigens, Le(x), sialylated Le(x) (SLEX), Le(a), and sialylated Le(a) (SLEA). Of the 92 lung cancers examined for antigen expression SLEX was detected in 57% (52 cases), Le(x) in 42% (39), SLEA in 36% (33), and Le(a) in 23% (21). None of these antigens were e...

background at altnagelvin, a district general hospital in northern ireland, we have observed that a significant number of hip fracture admissions are later readmitted for treatment of other medical conditions. these readmissions place increasing stress on the already significant burden that orthopedic trauma poses on national health services. objectives the aim of this study was to review a ser...

BACKGROUND Lewis y antigen is difucosylated oligosaccharide and is carried by glycoconjugates at cell surface. Elevated expression of Lewis y has been found in 75% of ovarian tumor, and the high expression level is correlated to the tumor's pathological staging and prognosis. This study was to investigate the effect and the possible mechanism of Lewis y on the proliferation of human ovarian can...

By employing a chiral Lewis base as the catalyst, enantioselective hydrosilylation of N-(1,2-diarylethylidene)arylamines was realized. The reactions proceeded smoothly to afford various chiral 1,2-diarylethanamines with good yields (up to 99%) in good enantioselectivities (up to 98%). Furthermore, one of the products was employed in the synthesis of a pharmaceutical substance.

Progeny-test (PT) programs of US artificial-insemination (AI) organizations were examined to determine timeliness of sampling, PT daughter distribution, rate of return of PT bulls to widespread service, and genetic merit of PT bulls compared with AI-proven and natural-service (NS) bulls. Bull age at semen release and at birth and calving of PT daughters was documented by breed (Ayrshire, Brown ...

Hip fracture is the most devastating osteoporotic fracture type with significant morbidity and mortality. Several studies in humans and animal models identified chromosomal regions linked to hip size and bone mass. Previously, we identified that the region of 4q21-q41 on rat chromosome (Chr) 4 harbors multiple femoral neck quantitative trait loci (QTLs) in inbred Fischer 344 (F344) and Lewis (L...

We established a new congenic model of hypertension, the mRen(2). Lewis rat and assessed the intracellular expression of angiotensin peptides and receptors in the kidney. The congenic strain was established from the backcross of the (mRen2)27 transgenic rat that expresses the mouse renin 2 gene onto the Lewis strain. The 20-wk-old male congenic rats were markedly hypertensive compared with the ...