In heterogeneous network environments, the network connections of a multi-homed device may have significant bandwidth differential. For a multihomed transmission protocol designed for network failure tolerance, such as SCTP, path selection algorithms for data transmission drastically affect performance. This article studies the effect of path bandwidth differential on the performance of retrans...

In a syngeneic murine model of multiple myeloma with many of the characteristics of the human disease, a monoclonal antibody (mAb) to the integrin very late antigen-4 (VLA-4), given after the myeloma has already homed to and begun to establish itself within the bone marrow compartment, produces statistically significant effects on multiple disease variables. These include reductions in circulat...

Beyond 3G (B3G) environments typically consist of multi-homed terminals and wireless overlay networks. This paper presents a categorization of IP-level mobility management solutions for B3G environments. Closely observing the mobility requirements of a wide range of possible applications, the paper also motivates the consideration of a new mobility management approach in B3G environments, where...

In future generations of wireless networks, it is expected that different users with various multi-homed personal wireless devices will have the option of accessing their desired services via different available radio access networks. Given the variability of the radio environment properties and user mobility, the availability and characteristics of an access network will change in time and are...

Human Wharton's jelly-derived mesenchymal stem cells (hWJ-MSCs) have excellent proliferative ability, differentiation ability, low immunogenicity, and can be easily obtained. However, there are few studies on their application in the treatment of ischemic stroke, therefore their therapeutic effect requires further verification. In this study, hWJ-MSCs were transplanted into an ischemic stroke r...

We performed combinatorial peptide library screening in vivo on a novel human prostate cancer xenograft that is androgen-independent and induces a robust osteoblastic reaction in bonelike matrix and soft tissue. We found two peptides, PKRGFQD and SNTRVAP, which were enriched in the tumors, targeted the cell surface of androgen-independent prostate cancer cells in vitro, and homed to androgen re...

In the case of next generation wireless networks, different users with various multi-homed personal wireless devices will aim to exploit the full potential of the choice of services and applications available over different radio access networks. In their selection of a certain radio access network consumers will consider money and delay preferences for the current application and will rely on ...

Abstract Background Majority of neuroblastoma patients develop metastatic disease at diagnosis and their prognosis is poor with current therapeutic approach. Major challenges are how to tackle the mechanisms responsible for tumorigenesis metastasis. Human mesenchymal stem cells (hMSCs) may be actively involved in constitution cancer microenvironment. Methods An orthotopic murine model was utili...

The advent of multi-technologies networks offering the service continuum over multiple network infrastructures implies new challenges to integrated management. One of this challenge is the auto-configuration of the management plane needed to allow dynamic relationships among several managers and one management agent. This paper proposes the use of provisional policies in order to dynamically au...