OBJECTIVE The present study was aimed to investigate the impact of postoperative pituitary tumor adrenal insufficiency and hormone replacement therapy (HRT) on tumor recurrence. PATIENTS AND METHODS The prospective study included 143 pituitary tumor patients as study subjects. Within 6 months after the operation, the study was planned to explore differences (if any) between the tumor recurren...

. Cardiovascular disease is the number-one killer of women in the Western world. . The public, and many physicians, have a very low awareness of the relevance of cardiovascular disease to menopausal women. . The public and many physicians are concerned that menopausal treatments (particularly hormonal therapies) increase the risk of cardiovascular disease, despite recent evidence showing that, ...

OBJECTIVE To assess the risk of adverse cardiovascular events in women who discontinue hormone replacement therapy after myocardial infarction compared with those who continue. DESIGN Nationwide register based cohort study. SETTING All hospitals in Denmark. POPULATION All 3322 women aged 40 years or over who survived 30 days after a myocardial infarction and were prescribed hormone replac...

OBJECTIVE To investigate the risk of ischaemic heart disease and myocardial infarction among women using hormone replacement therapy, especially the potential modifying effect of cardiovascular risk factors. DESIGN Prospective observational study. SETTING Denmark. PARTICIPANTS 19 898 nurses aged 45 and over completing a questionnaire on lifestyle and use of hormone replacement therapy in ...

OBJECTIVE To find out perimenopausal women's views on taking hormone replacement therapy to prevent osteoporosis. DESIGN Semistructured postal questionnaire survey; the questionnaire was enclosed with a letter to explain the purpose of the study and to give patients some information about hormone replacement therapy and osteoporosis. SETTING Mixed social class, urban general practice with 1...

OBJECTIVE To assess whether risk factor profiles for cardiovascular disease differed, before starting treatment, between women who would subsequently use hormone replacement therapy and those who would remain untreated. DESIGN Prospective population study, initiated in 1968-9, with follow ups in 1974, 1980, and 1992. SETTING Gothenburg, Sweden. PARTICIPANTS 1201 women born in 1918, 1922, ...