PURPOSE/OBJECTIVES To evaluate the intermediate term efficacy and toxicity of the use of venlafaxine for the control of hot flashes. DESIGN An open-label continuation phase study following a double-blind, randomized, placebo-controlled clinical trial that tested three doses of venlafaxine for the control of hot flashes. SETTING North Central Cancer Treatment Group institutions. SAMPLE 102...

objective: the beneficial effects of clove on toothache have been well documented. we have also previously shown the analgesic effects of clove essential oil. the present work was done to investigate the analgesic effects of the aqueous extract of clove using hot plate test. the possible role of opioid receptors in the analgesic effects of clove was also investigated using naloxone. materials a...

morphine and tramadol which have analgesic effects can be administered acutely or chronically. this study tried to investigate the effect of these drugs at various times by using different methods of administration (intraperitoneal, oral, acute and chronic). sixty adult female rats were divided into six groups. they received saline, morphine or tramadol (20 to 125 mg/kg) daily for 15 days. a ho...

objective(s):reduction of pharmacological effectiveness or tolerance appears following repeated administration of many analgesic drugs. we investigated tolerance to anti-nociceptive effects of orexin-a, an endogenous potent analgesic peptide using the hot-plate test.materials and methods:orexin-a was microinjected icv (intracerebroventricular) with an interval of 12 hr for 7 continuous days and...

introduction natural and artificial radionuclides are the main sources of human radiation exposure. these radionuclides, which are present in the environment, can be dissolved into water. evidence suggests that radionuclides being entered the human body through drinking or hot spring water can be harmful for human health. materials and methods in this study,10 samples were collected from ground...

Hot flashes are experienced by over 70% of menopausal women. Criteria to classify hot flashes from physiologic signals show variable performance. The primary aim was to compare conventional criteria to Support Vector Machines (SVMs), an advanced machine learning method, to classify hot flashes from sternal skin conductance. Thirty women with > or =4 hot flashes/day underwent laboratory hot flas...

We use new and archival Chandra data to investigate the X-ray emission from a large sample of compact hot spots of FR II radio galaxies and quasars from the 3C catalog. We find that only the most luminous hot spots tend to be in good agreement with the predictions of a synchrotron self-Compton model with equipartition magnetic fields. At low hot spot luminosities inverse Compton predictions are...

Hot electrons generated through plasmonic excitations in metal nanostructures show great promise for efficiently driving chemical reactions with light. However, the lifetime, yield, and mechanism of action of plasmon-generated hot electrons involved in a given photocatalytic process are not well understood. Here, we develop ultrafast surface-enhanced Raman scattering (SERS) as a direct probe of...

-1. The effect of ambient temperature on frequency, intensity and duration of hot flashes was studied in six women with hot flashes who were exposed to cool (T a = 19°C) and warm (ira = 31°C) /'as for 8-h periods. Heart rate, skin resistance, core and skin temperatures, subjective hot flash intensity and duration were recorded. 2. In the cool T~ as compared with the warm Ta, hot flashes were si...