Objective: Infection with various types of HPV has a causal relationship with thedevelopment of cervical cancer and other anogenital diseases. A prophylactic quadrivalent HPVvaccination has been produced. Here the pathophysiology of HPV infection and results ofmultiple HPV vaccine studies are discussed to determine efficacy and immunogenicity.Methods: The review includes art...

PURPOSE Potential barriers to widespread vaccination of adolescent girls against human papillomavirus (HPV) infection are poorly understood. We provide an overview of potential barriers to provision of HPV vaccine and empirical data on the concerns of medical practices that may inhibit HPV vaccine provision. METHOD We conducted phone interviews with medical practices in rural areas in southea...

OBJECTIVE To determine correlates of human papillomavirus (HPV) vaccine acceptance in mid-adult women. METHODS A convenience sample of 472 mid-adult women completed a 2-part, 69-item survey that included demographic, knowledge, and behavioral variables as potential correlates of vaccine acceptance. Univariable and multivariable logistic regression models were used to identify correlates for v...

A registry-based follow-up of pregnancy data until the end 2014 was conducted based on a community-randomized trial to assess human papillomavirus (HPV) vaccination strategies and reference cohort from same community with no intervention. Our objective determine whether prophylactic HPV (three doses Cervarix® (AS04-HPV-16/18)-vaccine) affects preterm birth (PTB) rates. All identified 80,272 res...

BACKGROUND Women with SLE have higher rates of persistent human papilloma virus (HPV) infections and precancerous lesions than healthy women. HPV vaccine is safe and effective in healthy females aged 9-26 years. There are limited data on the safety and immunogenicity of HPV vaccine in females with SLE, and none in adolescents with SLE. Our study evaluates the safety and immunogenicity of recomb...

BACKGROUND Although over a hundred million dollars have been invested in offering free quadrivalent human papillomavirus (HPV) vaccination to young girls in Ontario, there continues to be very little information about its usage. In order to successfully guide future HPV vaccine programming, it is important to monitor HPV vaccine use and determine factors associated with use in this population. ...

BACKGROUND Improving the quality of physicians' recommendations for human papillomavirus (HPV) vaccination is critical to addressing low coverage. Thus, we sought to describe HPV vaccine communication practices among primary care physicians. METHODS Pediatricians and family physicians (n = 776) completed our national online survey in 2014. We assessed the quality of their HPV vaccine recommen...

background: cervical cancer is the most prevalent tumor in developing countries and the second most frequent cancer among female population worldwide. specific human papillomaviruses and, most notably, hpv types 16 and 18 are recognized as being caus-ally associated with cervical carcinomas. the early hpv type 16 genes, e6 and e7, di-rectly participate in the in vitro transformation of primary ...

BACKGROUND The duration of protection afforded by vaccines represents a critical test of their utility as public health interventions. Some vaccines induce long-term immunity, while others require booster doses. Vaccines that induce long-term protection are usually characterized by the generation of immune memory. Recent trials of a quadrivalent (types 6, 11, 16, 18) human papillomavirus (HPV) ...

Background/Purpose: HPV vaccine is critical in the primary prevention of infection and related diseases. vaccination alone reduces by 70% cervical cancer 48%. Healthcare workers are expected to have sufficient knowledge positive attitudes behaviours about vaccine. This study aimed determine level healthcare their beliefs barriers towards vaccination. 
 Methods: In this cross-sectional stud...