Background Telestroke is recognized as a safe and time-efficient way of treating stroke patients. However, admission centers (spokes) are subject to financial charges which can make them reluctant to join the system. We implemented and assessed an economic model supporting our telestroke system, Virtuall, France, which includes one expert center (hub) and six spokes. Methods The model is base...

Considering the hub airports are traffic transfer points, the congestion is easily happened. The cost caused by congestion will rise significantly. The hub-and-spoke airline network optimization model with congestion cost is designed. In the actual operations of airlines, such problem is difficult to be solved by using the classical optimization methods. This paper presents a Particle Swarm Opt...

These papers are produced by Cambridge Judge Business School, University of Cambridge. They are circulated for discussion purposes only. Their contents should be considered preliminary and are not to be quoted without the authors' permission. The stochastic uncapacitated single allocation p-hub center problem is an extension of the deter-ministic version which aims to minimize the longest origi...

This paper considers the locational effects of geographically discriminatory trade policy. A preferential move towards a free trade area pulls industry into the integrating countries. Input-output links between imperfectly competitive firms amplify this effect and, when trade barriers fall below some critical level, may lead to agglomeration with some member countries gaining industry at the ex...

Quantum repeaters are critical to the development of quantum networks, enabling rates entanglement distribution beyond those attainable by direct transmission. We consider multiple continuous-variable, squeezed light-based flows through a repeater involving noiseless linear amplification and dual homodyne detection. By analyzing single-repeater-enhanced channel model with asymmetric half-channe...

Hub facilities serve as switching and transshipment points in transportation and communication networks as well as in logistic systems. Hub networks have an influence on flows on the hub-to-hub links and ensure benefit from economies of scale in inter-hub transportation. The key factors for designing a successful hub-and-spoke network are to determine the optimal number of hubs, to properly loc...