To encourage re-establishment of functional innervation of ipsilateral lumbar motoneurons by descending fibers after an intervening lateral thoracic (T10) hemisection (Hx), we treated adult rats with the following agents: (i) anti-Nogo-A antibodies to neutralize the growth-inhibitor Nogo-A; (ii) neurotrophin-3 (NT-3) via engineered fibroblasts to promote neuron survival and plasticity; and (iii...

We determined the acute effects of oxidative stress on glucose uptake and intracellular signaling in skeletal muscle by incubating muscles with reactive oxygen species (ROS). Xanthine oxidase (XO) is a superoxide-generating enzyme that increases ROS. Exposure of isolated rat extensor digitorum longus (EDL) muscles to Hx/XO (Hx/XO) for 20 min resulted in a dose-dependent increase in glucose upta...

This article seeks to broaden emotional labor research through the lens of a Human Experience (HX) perspective, in contrast either an Employee (EX) or Customer (CX) perspective. In services, HX perspective explicitly acknowledges that both employees and customers are humans with same set basic human needs gratify their Moment Truth (MOT) interactions. The focus here is on parties’ for authentic...

To search for submolecular foldon units, the spontaneous reversible unfolding and refolding of staphylococcal nuclease under native conditions was studied by a kinetic native-state hydrogen exchange (HX) method. As for other proteins, it appears that staphylococcal nuclease is designed as an assembly of well-integrated foldon units that may define steps in its folding pathway and may regulate s...

One of the earliest steps in animal embryogenesis involves establishing the identity of embryonic structures and tissues from head to tail along the anterior-posterior axis. Hox genes encode a family of proteins that have a prominent and broadly conserved role in laying out this developmental roadmap in most animals. For some time, it’s been felt that Hox function was fairly well understood: a ...

The amide hydrogen-deuterium exchange (HX) in the Src homology region 3 (SH3) domain of alpha-spectrin has been measured by nuclear magnetic resonance as a function of temperature between 8 and 46 degrees C. The analysis of the temperature dependence of HX from a statistical thermodynamic point of view has allowed us to estimate the enthalpies and entropies of the conformational processes leadi...

I cast 3-D data regularization as a least-squares inversion problem. The model space is a four-dimensional (t , cmpx , cmpy ,hx ) hypercube. An interpolation operator maps to an irregular five dimensional space (t , cmpx , cmpy ,hx ,h y) which is then mapped back into a four dimensional space by applying Azimuth Move-Out (AMO). A regularization term minimizes the difference between various (t ,...

For a topological dynamical system (X, f), consisting of a continuous map f : X → X, and a (not necessarily compact) set Z ⊂ X, Bowen [2] defined a dimension-like version of entropy, hX(f, Z). In the same work, he introduced a notion of entropyconjugacy for pairs of invertible compact systems: the systems (X, f) and (Y, g) are entropy-conjugate if there exist invariant Borel sets X ′ ⊂ X and Y ...